Record in detail
General Info
- lamp_id:L01A000016
- Name:MASTA_VESMG
- FullName:Mastoparan-like peptide 12a
- Source:Vespa magnifica
- Mass:1557 Da
- Sequence Length:14 aa
- Isoelectric Point:11.1
- Activity:Antibacterial, Antifungal
- Sequence
INWKGIAAMAKKLL - Function:Mast cell degranulating peptide. Has little hemolytic activity. Shows antimicrobial activity against the Gram-negative bacteria E.coli ATCC 25922 (MIC=7.5 ug/ml), the Gram-positive bacteria S.aureus ATCC 2592 (MIC=3.7 ug/ml) and the fungus C.albicans ATCC 2002 (MIC=3.7 ug/ml).
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ14
- 2 Database:DBAASP 1564
- 3 Database:dbAMP dbAMP_04811
- 4 Database:DRAMP DRAMP03033
- 5 Database:SATPdb satpdb24555
- 6 Database:Uniprot P0C1M4
- 7 Database:AMD MAST_VESXA
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000016 From 1 To 14 E-value: 0.014 Score: 29.3
INWKGIAAMAKKLL - 2. L11A012969 From 1 To 13 E-value: 0.039 Score: 27.7
INWKGIAAMAKKL - 3. L13A024089 From 1 To 13 E-value: 0.041 Score: 27.7
INWKGIAAMAKKL - 4. L11A012973 From 1 To 13 E-value: 0.041 Score: 27.7
INWKGIAAMAKKL - 5. L11A012968 From 2 To 14 E-value: 0.041 Score: 27.7
NWKGIAAMAKKLL
Activity
- Antibacterial Activities
- 1 Target: E. coli ATCC 25922 MIC: 7.5 μg/ml (4.81696 μM)
- 2 Target: S. aureus ATCC 2592 MIC: 3.7 μg/ml (2.37636 μM)
- 3 Target: C. albicans ATCC 2002 MIC: 3.7 μg/ml (2.37636 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lai R.,Li J.,Yu H.,Yang H.,Xu X.,
- Title:The mastoparanogen from wasp.
- Journal:Peptides, 2006, 27, 3053-3057 [PubMed:17046111]
- [2] Zhang Y.,Yang H.,Lu Q.,Li J.,Xu X.,
- Title:Two families of antimicrobial peptides from wasp (Vespa magnifica) venom.
- Journal:Toxicon, 2006, 47, 249-253 [PubMed:16330062]
Comments
- Comments
No comments found on LAMP database