Record in detail
General Info
- lamp_id:L01A000017
- Name:MASTB_POLDO
- FullName:Dominulin-B
- Source:Polistes dominula
- Mass:1911.3 Da
- Sequence Length:17 aa
- Isoelectric Point:10.51
- Activity:Antibacterial
- Sequence
INWKKIAEIGKQVLSAL - Function:Shows antimicrobial activity against the Gram-positive bacteria B.subtilis ATCC 6633 (MIC=2 ug/ml), and the Gram-negative bacteria E.coli JM109 (MIC=8 ug/ml).
Cross-Linking
- Cross-linking
- 1 Database:APD 1639
- 2 Database:CAMP CAMPSQ15
- 3 Database:DBAASP 503
- 4 Database:dbAMP dbAMP_04813
- 5 Database:DRAMP DRAMP03051
- 6 Database:SATPdb satpdb21818
- 7 Database:Uniprot P0C1M7
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000017 From 1 To 17 E-value: 0.0003 Score: 35
INWKKIAEIGKQVLSAL - 2. L13A019087 From 1 To 16 E-value: 0.001 Score: 33.5
INWKKIAEIGKQVLSA - 3. L02A001637 From 1 To 17 E-value: 0.011 Score: 30
INWKKIASIGKEVLKAL - 4. L01A000015 From 1 To 17 E-value: 0.019 Score: 29.3
INWKKIAEVGGKILSSL - 5. L13A023670 From 1 To 17 E-value: 0.023 Score: 28.9
INWKKIASIGKEVLKAI
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: B. subtilis ATCC 6633 MIC: 2 μg/ml (1.04641 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Pieraccini G.,Moneti G.,Dani F.R.,Mastrobuoni G.,Turillazzi S.,
- Title:Dominulin A and B: two new antibacterial peptides identified on the cuticle and in the venom of the social paper wasp Polistes dominulus using MALDI-TOF, MALDI-TOF/TOF, and ESI-ion trap.
- Journal:J. Am. Soc. Mass Spectrom., 2006, 17, 376-383 [PubMed:16446098]
Comments
- Comments
No comments found on LAMP database