Record in detail
General Info
- lamp_id:L01A000029
- Name:ACBP_PIG
- FullName:Acyl-CoA-binding protein
- Source:Sus scrofa
- Mass:6150.1 Da
- Sequence Length:55 aa
- Isoelectric Point:10.14
- Activity:Antibacterial
- Sequence
KQATVGDINTERPGILDLKGKAKWDAWNGLKGTSKEDAMKAYINKVEELKKKYGI - Function:Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ27
- 2 Database:dbAMP dbAMP_05241
- 3 Database:DRAMP DRAMP02966
- 4 Database:Uniprot P12026
- 5 Database:AMD DBIF_PIG
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A09389| From 33 To 87 E-value: 3e-27 Score: 112
KQATVGDINTERPGILDLKGKAKWDAWNGLKGTSKEDAMKAYINKVEELKKKYGI - 2. L01A000029 From 1 To 55 E-value: 1e-26 Score: 110
KQATVGDINTERPGILDLKGKAKWDAWNGLKGTSKEDAMKAYINKVEELKKKYGI
Activity
- Antibacterial Activities
- 1 Target: B. megaterium Bmll MIC: 4.24 μg/ml (0.68942 μM)
- 2 Target: E. coli. D22 MIC: 184.5 μg/ml (29.9995 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Mutt V.,Andersson M.,Gell K.,Agerberth B.,Chen Z.W.,
- Title:Isolation and characterization of porcine diazepam-binding inhibitor, a polypeptide not only of cerebral occurrence but also common in intestinal tissues and with effects on regulation of insulin release.
- Journal:Eur. J. Biochem., 1988, 174, 239-245 [MEDLINE:88254787]
- [2] Mutt V.,Joernvall H.,Andersson M.,Boman A.,Agerberth B.,
- Title:Isolation of three antibacterial peptides from pig intestine: gastric inhibitory polypeptide (7-42), diazepam-binding inhibitor (32-86) and a novel factor, peptide 3910.
- Journal:Eur. J. Biochem., 1993, 216, 623-629 [MEDLINE:93387315]
Comments
- Comments
No comments found on LAMP database