Record in detail
General Info
- lamp_id:L01A000031
- Name:CR110_LITSP
- FullName:Caerin-1.10
- Source:Litoria splendida
- Mass:2576.2 Da
- Sequence Length:25 aa
- Isoelectric Point:9.54
- Activity:Antibacterial,Anticancer
- Sequence
GLLSVLGSVAKHVLPHVVPVIAEKL - Function:Antibacterial peptide with wide spectrum of activity. Active against L.lactis, L.innocua, M.luteus, S.uberis and less against P.multocida and S.epidermidis.
Cross-Linking
- Cross-linking
- 1 Database:APD 345
- 2 Database:CAMP CAMPSQ29
- 3 Database:DBAASP 505
- 4 Database:dbAMP dbAMP_03659
- 5 Database:DRAMP DRAMP01577
- 6 Database:SATPdb satpdb13953
- 7 Database:Uniprot P82104
- 8 Database:AMD CR10_LITSP
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000031 From 1 To 25 E-value: 0.00000008 Score: 47.4
GLLSVLGSVAKHVLPHVVPVIAEKL - 2. L12A06177| From 50 To 74 E-value: 0.0000001 Score: 46.6
GLLSVLGSVAKHVLPHVVPVIAEHL - 3. L12A06176| From 50 To 74 E-value: 0.0000002 Score: 46.2
GLLSVLGSVAKHVLPHVVPVIAEHL - 4. L13A012508 From 1 To 24 E-value: 0.0000002 Score: 46.2
GLLSVLGSVAKHVLPHVVPVIAEK - 5. L13A010713 From 1 To 25 E-value: 0.0000002 Score: 46.2
GLLSVLGDVAKHVLPHVVPVIAEKL
Activity
- Antibacterial Activities
- 1 Target: L. lactis MIC: 6 μg/ml (2.32901 μM)
- 2 Target: L. innocua MIC: 50 μg/ml (19.4084 μM)
- 3 Target: M. luteus MIC: 25 μg/ml (9.70422 μM)
- 4 Target: S. uberis MIC: 50 μg/ml (19.4084 μM)
- 5 Target: P. multocida MIC: 100 μg/ml (38.8169 μM)
- 6 Target: S. epidermidis MIC: 100 μg/ml (38.8169 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Smith B.P.,Wallace J.C.,Tyler M.J.,Bowie J.H.,Wabnitz P.A.,
- Title:Differences in the skin peptides of the male and female Australian tree frog Litoria splendida. The discovery of the aquatic male sex pheromone splendipherin, together with Phe8 caerulein and a new antibiotic peptide caerin 1.10.
- Journal:Eur. J. Biochem., 2000, 267, 269-275 [MEDLINE:20069371]
Comments
- Comments
No comments found on LAMP database