Record in detail

General Info

lamp_id:L01A000032
Name:TEMA_RANTE
FullName:Temporin-A
Source:Rana temporaria
Mass:1397.7 Da
Sequence Length:13 aa
Isoelectric Point:10.55
Activity:Antibacterial
Sequence
FLPLIGRVLSGIL
Function:Has antibacterial activity against Gram-positive bacteria.

Cross-Linking

Cross-linking
1 Database:APD 94
2 Database:CAMP CAMPSQ30
3 Database:DBAASP 506
4 Database:dbAMP dbAMP_02102
5 Database:DRAMP DRAMP01730
6 Database:SATPdb satpdb12693
7 Database:Uniprot P56917
8 Database:AMD TMPA_RANTE

Top similar AMPs

Top similar AMPs on LAMP
1. L11A007151 From 1 To 13 E-value: 0.082 Score: 26.6
FLPLIGRVLSGIL
2. L01A000032 From 1 To 13 E-value: 0.088 Score: 26.6
FLPLIGRVLSGIL
3. L01A000036 From 1 To 13 E-value: 0.17 Score: 25.4
FLPLIGKVLSGIL
4. L13A025273 From 1 To 13 E-value: 0.17 Score: 25.4
FLPLIGRVLAGIL
5. L13A010103 From 1 To 12 E-value: 0.17 Score: 25.4
FLPLIGRVLSGI

Structure

Domains

Structures

Activity

Antibacterial Activities
1 Target: B. megateriurn Bml I MIC: 1.68 μg/ml (1.20197 μM)
2 Target: S. aureus Cowanl MIC: 3.21 μg/ml (2.29663 μM)
3 Target: Y. pseudotuberculosis MIC: 2.8 μg/ml (2.00329 μM)
4 Target: S. pyogenes/3 hem. group A MIC: 2.8 μg/ml (2.00329 μM)
5 Target: E. coli D21 MIC: 16.63 μg/ml (11.8981 μM)
6 Target: P. aeruginosa ATCC15692 MIC: 503.17 μg/ml (359.999 μM)
7 Target: C. albicans MIC: 4.75 μg/ml (3.39844 μM)

Toxicity

Toxicity

Reference

Reference
[1] Mangoni M.L.,Miele R.,Canofeni S.,Mignogna G.,Simmaco M.,
Title:Temporins, antimicrobial peptides from the European red frog Rana temporaria.
Journal:Eur. J. Biochem., 1996, 242, 788-792 [MEDLINE:97175050]

Comments

Comments