Record in detail

lamp_id:L01A000042
Name:BMNL2_BOMOR
FullName:Bombinin-like peptide 2
Source:Bombina orientalis
Mass:2582 Da
Sequence Length:27 aa
Isoelectric Point:10.51
Activity:Antibacterial, Antifungal
Sequence
GIGSAILSAGKSALKGLAKGLAEHFAN
Function:Has antimicrobial activity, but no hemolytic activity. Preference on killing Gram-negative non-enteric bacteria.

Top similar AMPs on LAMP
1. L01A000042 From 1 To 27 E-value: 0.000000008 Score: 50.8
GIGSAILSAGKSALKGLAKGLAEHFAN
2. L01A000041 From 1 To 27 E-value: 0.00000004 Score: 48.5
GIGASILSAGKSALKGLAKGLAEHFAN
3. L01A000004 From 1 To 27 E-value: 0.00000007 Score: 47.8
GIGGALLSAGKSALKGLAKGLAEHFAN
4. L01A000231 From 1 To 27 E-value: 0.00000009 Score: 47.4
GIGASILSAGKSALKGFAKGLAEHFAN
5. L13A028087 From 1 To 27 E-value: 0.0000002 Score: 46.6
GIGGALLSAGKSALKGLAKGLADHFAN

Antibacterial Activities
1 Target: 58 % inhibition Neisseria meningitidis 118V C MIC: 20 μg/ml (7.74593 μM)
2 Target: 98 % inhibition Neisseria meningitidis 15240 IAI MIC: 20 μg/ml (7.74593 μM)
3 Target: 98% inhibition Neisseria meningitidis 126E IC1 MIC: 20 μg/ml (7.74593 μM)
4 Target: 97% inhibition Neisseria gonorrhoeoe F62 MIC: 20 μg/ml (7.74593 μM)
5 Target: 99% inhibitionNeisseria Iactamica 15323 MIC: 20 μg/ml (7.74593 μM)
6 Target: 100% inhibition Neisseria Iactamica 15215A MIC: 20 μg/ml (7.74593 μM)
7 Target: 95% inhibition Neisseria cinerea 15461 MIC: 20 μg/ml (7.74593 μM)

Reference
[1] Spindel E.R.,Kelly M.,Mandrell R.,Tang D.,Gibson B.W.,
Title:Bombinin-like peptides with antimicrobial activity from skin secretions of the Asian toad, Bombina orientalis.
Journal:J. Biol. Chem., 1991, 266, 23103-23111 [MEDLINE:92078177]