Record in detail


General Info

  • lamp_id:L01A000048
  • Name:LAT2B_LACTA
  • FullName:M-zodatoxin-Lt2b
  • Source:Lachesana tarabaevi
  • Mass:2879.5 Da
  • Sequence Length:26 aa
  • Isoelectric Point:11.97
  • Activity:Antibacterial, Antifungal
  • Sequence
        GLFGKLIKKFGRKAISYAVKKARGKN
  • Function:Has antimicrobial activity against both Gram-positive and Gram-negative bacteria, and yeasts. Also has a strong hemolytic activity against rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A08392|    From 59 To 84 E-value: 0.00000001 Score: 50.4
        GLFGKLIKKFGRKAISYAVKKARGKH
  • 2. L01A000048    From 1 To 26 E-value: 0.00000002 Score: 50.1
        GLFGKLIKKFGRKAISYAVKKARGKN
  • 3. L01A000047    From 1 To 26 E-value: 0.00000005 Score: 48.1
        GLFGKLIKKFGRKAISYAVKKARGKH
  • 4. L13A023171    From 1 To 26 E-value: 0.0000002 Score: 46.6
        GLFGKLIKKFARKAISYAVKKARGKH
  • 5. L13A014628    From 1 To 26 E-value: 0.0000003 Score: 45.8
        GLFGKLQKKFGRKAISYAVKKARGKH

Structure

  •   Domains
  •   1  Name:Latarcin_precursor    Interpro Link:IPR018802
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Karpunin D.V.,Surovoy A.Y.,Feofanov A.V.,Vassilevski A.A.,Kozlov S.A.,
  •   Title:Latarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity.
  •   Journal:J. Biol. Chem., 2006, 281, 20983-20992  [PubMed:16735513]

Comments

  •   Comments

    •     No comments found on LAMP database



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