Record in detail


General Info

  • lamp_id:L01A000055
  • Name:GANOD_GANLU
  • FullName:Ganodermin
  • Source:Ganoderma lucidum
  • Mass:2729.2 Da
  • Sequence Length:27 aa
  • Isoelectric Point:11.08
  • Activity:Antifungal
  • Sequence
        AGETHTVMINHAGRGAPKLVVGGKKLS
  • Function:Has antifungal activity against B.cinera, F.oxysporum and P.piricola with IC(50) values of 15.2 uM, 12.4 uM and 18.1 uM, respectively. Lacks hemagglutinating activity towards rabbit erythrocytes. Lacks deoxyribonuclease, ribonuclease and protease inhibitory activities.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000055    From 1 To 27 E-value: 0.0000000003 Score: 55.5
        AGETHTVMINHAGRGAPKLVVGGKKLS

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Botrytis cinerea  IC50:  41.48 μg/ml  (15.1986 μM)  
  •   2  Target:  Fusarium oxysporum  IC50:  33.84 μg/ml  (12.3992 μM)  
  •   3  Target:  Physalospora piricola  IC50:  49.4 μg/ml  (18.1005 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Ng T.B.,Wang H.,
  •   Title:Ganodermin, an antifungal protein from fruiting bodies of the medicinal mushroom Ganoderma lucidum.
  •   Journal:Peptides, 2006, 27, 27-30  [PubMed:16039755]

Comments

  •   Comments

    •     No comments found on LAMP database



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