Record in detail

lamp_id:L01A000064
Name:CECB_HYACE
FullName:Cecropin-B
Source:Hyalophora cecropia
Mass:3835.7 Da
Sequence Length:35 aa
Isoelectric Point:11.49
Activity:Antibacterial
Sequence
KWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAL
Function:Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.

Top similar AMPs on LAMP
1. L03A000213 From 27 To 61 E-value: 0.00000000000002 Score: 69.7
KWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAL
2. L01A000064 From 1 To 35 E-value: 0.00000000000004 Score: 68.6
KWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAL
3. L01A001114 From 1 To 35 E-value: 0.00000000000005 Score: 68.2
KWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAL
4. L13A028862 From 1 To 35 E-value: 0.00000000000007 Score: 67.8
KWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAI
5. L13A011163 From 1 To 35 E-value: 0.00000000000007 Score: 67.8
KWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAI

Antibacterial Activities
1 Target: Refer :7140755 E. coli D21 LC: 1.23 μg/ml (0.320672 μM)
2 Target: E. coli D31 LC: 1.23 μg/ml (0.320672 μM)
3 Target: Serratia marcescens Db11 LC: 17.26 μg/ml (4.49983 μM)
4 Target: Serratia marcescens Db1108 LC: 9.21 μg/ml (2.40113 μM)
5 Target: Serratia marcescens Db1121 LC: 8.44 μg/ml (2.20038 μM)
6 Target: Serratia marcescens Strain 122 LC: 11.12 μg/ml (2.89908 μM)
7 Target: P. aeruginosa OT97 LC: 7.29 μg/ml (1.90057 μM)
8 Target: Xenorhabdus nematophilus Xn21 LC: 6.14 μg/ml (1.60075 μM)
9 Target: Bacillus megaterium Bmll LC: 1.69 μg/ml (0.440598 μM)
10 Target: B. subtilis Bs11 LC: 69.04 μg/ml (17.9993 μM)
11 Target: B. thuringiensis Bt11 LC: 510.15 μg/ml (133 μM)
12 Target: Streptococcus fecalis AD-4 LC: 28 μg/ml (7.29984 μM)
13 Target: Streptococcus fecalis DS16 LC: 92.06 μg/ml (24.0008 μM)
14 Target: Micrococcus luteus M111 LC: 4.99 μg/ml (1.30094 μM)

Reference
[1] Boman H.G.,Bennich H.,Engstroem A.,Hultmark D.,Steiner H.,
Title:Sequence and specificity of two antibacterial proteins involved in insect immunity.
Journal:Nature, 1981, 292, 246-248 [MEDLINE:81245158]
[2] Xanthopoulos K.G.,Lee J.-Y.,Kockum K.,Faye I.,van Hofsten P.,
Title:Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia.
Journal:Proc. Natl. Acad. Sci. U.S.A., 1985, 82, 2240-2243 [MEDLINE:85190472]
[3] Lee J.-Y.,Kockum K.,von Hofsten P.,Faye I.,Boman H.G.,
Title:On the primary structures of lysozyme, cecropins and attacins from Hyalophora cecropia.
Journal:Dev. Comp. Immunol., 1985, 9, 551-558 [MEDLINE:86005745]
[4] Faye I.,Kockum K.,Gan R.,Lee J.-Y.,Xanthopoulos G.,
Title:The structure of the gene for cecropin B, an antibacterial immune protein from Hyalophora cecropia.
Journal:Eur. J. Biochem., 1988, 172, 371-376 [MEDLINE:88166708]