Record in detail

lamp_id:L01A000071
Name:DFB12_BOVIN
FullName:Beta-defensin 12
Source:Bos taurus
Mass:4105.9 Da
Sequence Length:38 aa
Isoelectric Point:9.28
Activity:Antibacterial
Sequence
GPLSCGRNGGVCIPIRCPVPMRQIGTCFGRPVKCCRSW
Function:Has bactericidal activity. Active against E.coli ML35 and S.aureus 502A.

Top similar AMPs on LAMP
1. L03A000261 From 23 To 60 E-value: 1e-17 Score: 80.1
GPLSCGRNGGVCIPIRCPVPMRQIGTCFGRPVKCCRSW
2. L01A000072 From 5 To 42 E-value: 9e-17 Score: 77.4
GPLSCGRNGGVCIPIRCPVPMRQIGTCFGRPVKCCRSW
3. L01A000071 From 1 To 38 E-value: 1e-16 Score: 76.6
GPLSCGRNGGVCIPIRCPVPMRQIGTCFGRPVKCCRSW
4. L12A09071| From 27 To 64 E-value: 2e-16 Score: 75.9
GPLSCGRNGGVCIPIRCPVPMRQIGTCFRRPVKCCRSW
5. L12A00451| From 1 To 38 E-value: 3e-16 Score: 75.9
APLSCGRNGGVCIPIRCPVPMRQIGTCFGRPVKCCRSW

Reference
[1] Selsted M.E.,Tang Y.-Q.,
Title:Characterization of the disulfide motif in BNBD-12, an antimicrobial beta-defensin peptide from bovine neutrophils.
Journal:J. Biol. Chem., 1993, 268, 6649-6653 [MEDLINE:93203265]
[2] Novotny M.J.,McGuire P.A.,Morris W.L.,Tang Y.-Q.,Selsted M.E.,
Title:Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
Journal:J. Biol. Chem., 1993, 268, 6641-6648 [MEDLINE:93203264]
[3] Pardi A.,Selsted M.E.,Legault P.,Zimmermann G.R.,
Title:Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins.
Journal:Biochemistry, 1995, 34, 13663-13671 [MEDLINE:96027485]