Record in detail


General Info

  • lamp_id:L01A000076
  • Name:GGN1_GLARU
  • FullName:Gaegurin-1
  • Source:Glandirana rugosa
  • Mass:3462.1 Da
  • Sequence Length:33 aa
  • Isoelectric Point:10.3
  • Activity:Antibacterial, Antifungal, Antiparasitic
  • Sequence
        SLFSLIKAGAKFLGKNLLKQGACYAACKASKQC
  • Function:Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000076    From 1 To 33 E-value: 0.000000000001 Score: 63.9
        SLFSLIKAGAKFLGKNLLKQGACYAACKASKQC
  • 2. L01A000288    From 1 To 33 E-value: 0.00000000005 Score: 58.2
        SLFSLIKAGAKFLGKNLLKQGAQYAACKVSKEC
  • 3. L12A07228|    From 40 To 76 E-value: 0.0000003 Score: 45.8
        SIFSLFKAGAKFFGKNLLKEAGKAGAAHLACKATNQC
  • 4. L13A025266    From 1 To 37 E-value: 0.0000006 Score: 44.7
        SIFSLFKAGAKFFGKNLLKEAGKAGAAHLACKATNQC
  • 5. L12A07247|    From 41 To 76 E-value: 0.000001 Score: 43.5
        LFSILKIGAKVIGKNLLKQAGKAGMEYAACKATNQC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Micrococcus luteus  MIC:  5 μg/ml  (1.44421 μM)  
  •   2  Target:  Staphylococcus epidermidis  MIC:  50 μg/ml  (14.4421 μM)  
  •   3  Target:  Bacillus subtilis  MIC:  50 μg/ml  (14.4421 μM)  
  •   4  Target:  Klebsiella pneumoniae  MIC:  100 μg/ml  (28.8842 μM)  
  •   5  Target:  Shigella dysentariae  MIC:  25 μg/ml  (7.22105 μM)  
  •   6  Target:  Pseudomonas putida  MIC:  50 μg/ml  (14.4421 μM)  
  •   7  Target:  Pseudomonas aeruginosa  MIC:  50 μg/ml  (14.4421 μM)  
  •   8  Target:  Eshchericia coli  MIC:  25 μg/ml  (7.22105 μM)  
  •   9  Target:  Saccharomyces cerevisiae  MIC:  200 μg/ml  (57.7684 μM)  
  •   10  Target:  Candida albicans  MIC:  200 μg/ml  (57.7684 μM)  
  •   11  Target:  Salmonella typhimurium  MIC:  200 μg/ml  (57.7684 μM)  
  •   12  Target:  Proteus mirabilis  MIC:  200 μg/ml  (57.7684 μM)  
  •   13  Target:  Serratia marcescens  MIC:  200 μg/ml  (57.7684 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lee B.J.,Jung J.-E.,Park J.M.,
  •   Title:Antimicrobial peptides from the skin of a Korean frog, Rana rugosa.
  •   Journal:Biochem. Biophys. Res. Commun., 1994, 205, 948-954  [MEDLINE:95091844]

Comments

  •   Comments

  •     No comments found on LAMP database



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