Record in detail
General Info
- lamp_id:L01A000076
- Name:GGN1_GLARU
- FullName:Gaegurin-1
- Source:Glandirana rugosa
- Mass:3462.1 Da
- Sequence Length:33 aa
- Isoelectric Point:10.3
- Activity:Antibacterial, Antifungal, Antiparasitic
- Sequence
SLFSLIKAGAKFLGKNLLKQGACYAACKASKQC - Function:Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.
Cross-Linking
- Cross-linking
- 1 Database:APD 85
- 2 Database:CAMP CAMPSQ69
- 3 Database:DBAASP 5556
- 4 Database:dbAMP dbAMP_11109
- 5 Database:DRAMP DRAMP02291
- 6 Database:SATPdb satpdb16208
- 7 Database:Uniprot P80395
- 8 Database:AMD GAE1_RANRU
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000076 From 1 To 33 E-value: 0.000000000001 Score: 63.9
SLFSLIKAGAKFLGKNLLKQGACYAACKASKQC - 2. L01A000288 From 1 To 33 E-value: 0.00000000005 Score: 58.2
SLFSLIKAGAKFLGKNLLKQGAQYAACKVSKEC - 3. L12A07228| From 40 To 76 E-value: 0.0000003 Score: 45.8
SIFSLFKAGAKFFGKNLLKEAGKAGAAHLACKATNQC - 4. L13A025266 From 1 To 37 E-value: 0.0000006 Score: 44.7
SIFSLFKAGAKFFGKNLLKEAGKAGAAHLACKATNQC - 5. L12A07247| From 41 To 76 E-value: 0.000001 Score: 43.5
LFSILKIGAKVIGKNLLKQAGKAGMEYAACKATNQC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: Micrococcus luteus MIC: 5 μg/ml (1.44421 μM)
- 2 Target: Staphylococcus epidermidis MIC: 50 μg/ml (14.4421 μM)
- 3 Target: Bacillus subtilis MIC: 50 μg/ml (14.4421 μM)
- 4 Target: Klebsiella pneumoniae MIC: 100 μg/ml (28.8842 μM)
- 5 Target: Shigella dysentariae MIC: 25 μg/ml (7.22105 μM)
- 6 Target: Pseudomonas putida MIC: 50 μg/ml (14.4421 μM)
- 7 Target: Pseudomonas aeruginosa MIC: 50 μg/ml (14.4421 μM)
- 8 Target: Eshchericia coli MIC: 25 μg/ml (7.22105 μM)
- 9 Target: Saccharomyces cerevisiae MIC: 200 μg/ml (57.7684 μM)
- 10 Target: Candida albicans MIC: 200 μg/ml (57.7684 μM)
- 11 Target: Salmonella typhimurium MIC: 200 μg/ml (57.7684 μM)
- 12 Target: Proteus mirabilis MIC: 200 μg/ml (57.7684 μM)
- 13 Target: Serratia marcescens MIC: 200 μg/ml (57.7684 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lee B.J.,Jung J.-E.,Park J.M.,
- Title:Antimicrobial peptides from the skin of a Korean frog, Rana rugosa.
- Journal:Biochem. Biophys. Res. Commun., 1994, 205, 948-954 [MEDLINE:95091844]
Comments
- Comments
No comments found on LAMP database