Record in detail
General Info
- lamp_id:L01A000077
- Name:GGN2_GLARU
- FullName:Gaegurin-2
- Source:Glandirana rugosa
- Mass:3322 Da
- Sequence Length:33 aa
- Isoelectric Point:10.14
- Activity:Antibacterial, Antifungal, Antiparasitic
- Sequence
GIMSIVKDVAKNAAKEAAKGALSTLSCKLAKTC - Function:Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.
Cross-Linking
- Cross-linking
- 1 Database:APD 86
- 2 Database:CAMP CAMPSQ70
- 3 Database:DBAASP 5557
- 4 Database:dbAMP dbAMP_03121
- 5 Database:DRAMP DRAMP02292
- 6 Database:SATPdb satpdb27767
- 7 Database:Uniprot P80396
- 8 Database:AMD GAE2_RANRU
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000077 From 1 To 33 E-value: 0.000000000001 Score: 63.5
GIMSIVKDVAKNAAKEAAKGALSTLSCKLAKTC - 2. L01A003831 From 42 To 74 E-value: 0.0000005 Score: 44.7
GLMSTLKDFGKTAAKEIAQSLLSTASCKLAKTC - 3. L02A001896 From 1 To 33 E-value: 0.0000009 Score: 43.9
GLMSTLKDFGKTAAKEIAQSLLSTASCKLAKTC - 4. L01A000078 From 1 To 33 E-value: 0.00001 Score: 40
GIMSIVKDVAKTAAKEAAKGALSTLSCKLAKTC - 5. L01A003966 From 1 To 33 E-value: 0.00003 Score: 38.9
GLLDTLKNMAINAAKDAGVSVLNTLSCKLSKTC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: Micrococcus luteus MIC: 2.5 μg/ml (0.752559 μM)
- 2 Target: Staphylococcus epidermidis MIC: 10 μg/ml (3.01023 μM)
- 3 Target: Bacillus subtilis MIC: 10 μg/ml (3.01023 μM)
- 4 Target: Klebsiella pneumoniae MIC: 25 μg/ml (7.52559 μM)
- 5 Target: Shigella dysentariae MIC: 25 μg/ml (7.52559 μM)
- 6 Target: Pseudomonas putida MIC: 50 μg/ml (15.0512 μM)
- 7 Target: Pseudomonas aeruginosa MIC: 50 μg/ml (15.0512 μM)
- 8 Target: Eshchericia coli MIC: 75 μg/ml (22.5768 μM)
- 9 Target: Saccharomyces cerevisiae MIC: 150 μg/ml (45.1535 μM)
- 10 Target: Candida albicans MIC: 150 μg/ml (45.1535 μM)
- 11 Target: Salmonella typhimurium MIC: 150 μg/ml (45.1535 μM)
- 12 Target: Proteus mirabilis MIC: 200 μg/ml (60.2047 μM)
- 13 Target: Serratia marcescens MIC: 200 μg/ml (60.2047 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lee B.J.,Jung J.-E.,Park J.M.,
- Title:Antimicrobial peptides from the skin of a Korean frog, Rana rugosa.
- Journal:Biochem. Biophys. Res. Commun., 1994, 205, 948-954 [MEDLINE:95091844]
Comments
- Comments
No comments found on LAMP database