Record in detail
General Info
- lamp_id:L01A000079
- Name:GGN6_GLARU
- FullName:Gaegurin-6
- Source:Glandirana rugosa
- Mass:2610.2 Da
- Sequence Length:24 aa
- Isoelectric Point:8.79
- Activity:Antibacterial, Antifungal, Antiparasitic,Anticancer
- Sequence
FLPLLAGLAANFLPTIICKISYKC - Function:Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.
Cross-Linking
- Cross-linking
- 1 Database:APD 90
- 2 Database:CAMP CAMPSQ72
- 3 Database:DBAASP 2318
- 4 Database:dbAMP dbAMP_02117
- 5 Database:DRAMP DRAMP02296
- 6 Database:SATPdb satpdb22378
- 7 Database:Uniprot P80400
- 8 Database:AMD GAE6_RANRU
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000079 From 1 To 24 E-value: 0.00000002 Score: 49.7
FLPLLAGLAANFLPTIICKISYKC - 2. L12A07208| From 47 To 70 E-value: 0.0000002 Score: 46.2
FLPMLAGLAANFLPTIVCKITKKC - 3. L12A07168| From 48 To 71 E-value: 0.0000002 Score: 45.8
FLPLLAGLAANFLPQIICKIARKC - 4. L12A02116| From 1 To 24 E-value: 0.0000003 Score: 45.8
FLPLLAGLAANFLPTIICKIARKC - 5. L13A016693 From 1 To 24 E-value: 0.0000005 Score: 45.1
FLPMLAGLAANFLPTIVCKITKKC
Structure
- Domains
- 1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: Micrococcus luteus MIC: 2.5 μg/ml (0.957781 μM)
- 2 Target: Staphylococcus epidermidis MIC: 10 μg/ml (3.83112 μM)
- 3 Target: Bacillus subtilis MIC: 10 μg/ml (3.83112 μM)
- 4 Target: Klebsiella pneumoniae MIC: 50 μg/ml (19.1556 μM)
- 5 Target: Shigella dysentariae MIC: 50 μg/ml (19.1556 μM)
- 6 Target: Pseudomonas putida MIC: 50 μg/ml (19.1556 μM)
- 7 Target: Pseudomonas aeruginosa MIC: 100 μg/ml (38.3112 μM)
- 8 Target: Eshchericia coli MIC: 50 μg/ml (19.1556 μM)
- 9 Target: Saccharomyces cerevisiae MIC: 50 μg/ml (19.1556 μM)
- 10 Target: Candida albicans MIC: 50 μg/ml (19.1556 μM)
- 11 Target: Salmonella typhimurium MIC: 200 μg/ml (76.6225 μM)
- 12 Target: Proteus mirabilis MIC: 200 μg/ml (76.6225 μM)
- 13 Target: Serratia marcescens MIC: 200 μg/ml (76.6225 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lee B.J.,Jung J.-E.,Park J.M.,
- Title:Antimicrobial peptides from the skin of a Korean frog, Rana rugosa.
- Journal:Biochem. Biophys. Res. Commun., 1994, 205, 948-954 [MEDLINE:95091844]
Comments
- Comments
No comments found on LAMP database