Record in detail


General Info

  • lamp_id:L01A000079
  • Name:GGN6_GLARU
  • FullName:Gaegurin-6
  • Source:Glandirana rugosa
  • Mass:2610.2 Da
  • Sequence Length:24 aa
  • Isoelectric Point:8.79
  • Activity:Antibacterial, Antifungal, Antiparasitic,Anticancer
  • Sequence
        FLPLLAGLAANFLPTIICKISYKC
  • Function:Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000079    From 1 To 24 E-value: 0.00000002 Score: 49.7
        FLPLLAGLAANFLPTIICKISYKC
  • 2. L12A07208|    From 47 To 70 E-value: 0.0000002 Score: 46.2
        FLPMLAGLAANFLPTIVCKITKKC
  • 3. L12A07168|    From 48 To 71 E-value: 0.0000002 Score: 45.8
        FLPLLAGLAANFLPQIICKIARKC
  • 4. L12A02116|    From 1 To 24 E-value: 0.0000003 Score: 45.8
        FLPLLAGLAANFLPTIICKIARKC
  • 5. L13A016693    From 1 To 24 E-value: 0.0000005 Score: 45.1
        FLPMLAGLAANFLPTIVCKITKKC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_1    Interpro Link:IPR012520
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Micrococcus luteus  MIC:  2.5 μg/ml  (0.957781 μM)  
  •   2  Target:  Staphylococcus epidermidis  MIC:  10 μg/ml  (3.83112 μM)  
  •   3  Target:  Bacillus subtilis  MIC:  10 μg/ml  (3.83112 μM)  
  •   4  Target:  Klebsiella pneumoniae  MIC:  50 μg/ml  (19.1556 μM)  
  •   5  Target:  Shigella dysentariae  MIC:  50 μg/ml  (19.1556 μM)  
  •   6  Target:  Pseudomonas putida  MIC:  50 μg/ml  (19.1556 μM)  
  •   7  Target:  Pseudomonas aeruginosa  MIC:  100 μg/ml  (38.3112 μM)  
  •   8  Target:  Eshchericia coli  MIC:  50 μg/ml  (19.1556 μM)  
  •   9  Target:  Saccharomyces cerevisiae  MIC:  50 μg/ml  (19.1556 μM)  
  •   10  Target:  Candida albicans  MIC:  50 μg/ml  (19.1556 μM)  
  •   11  Target:  Salmonella typhimurium  MIC:  200 μg/ml  (76.6225 μM)  
  •   12  Target:  Proteus mirabilis  MIC:  200 μg/ml  (76.6225 μM)  
  •   13  Target:  Serratia marcescens  MIC:  200 μg/ml  (76.6225 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lee B.J.,Jung J.-E.,Park J.M.,
  •   Title:Antimicrobial peptides from the skin of a Korean frog, Rana rugosa.
  •   Journal:Biochem. Biophys. Res. Commun., 1994, 205, 948-954  [MEDLINE:95091844]

Comments

  •   Comments

  •     No comments found on LAMP database



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