Record in detail

lamp_id:L01A000088
Name:DIP_DROME
FullName:Diptericin
Source:Drosophila melanogaster
Mass:8902.7 Da
Sequence Length:83 aa
Isoelectric Point:6.8
Activity:Antibacterial
Sequence
DDMTMKPTPPPQYPLNLQGGGGGQSGDGFGFAVQGHQKVWTSDNGRHEIGLNGGYGQHLGGPYGNSEPSWKVGSTYTYRFPNF
Function:Required to resist Gram-negative bacterial infections, regulated by Dredd.

Top similar AMPs on LAMP
1. L01A000088 From 1 To 83 E-value: 1.96182e-44 Score: 169
DDMTMKPTPPPQYPLNLQGGGGGQSGDGFGFAVQGHQKVWTSDNGRHEIGLNGGYGQHLGGPYGNSEPSWKVGSTYTYRFPNF
2. L02A001565 From 1 To 83 E-value: 2.00386e-43 Score: 166
DDMTMKPTPPPQYPLNLQGGGGGGSGDGFGFAVQGHQKVWTSDNGRHEIGLNGGYGQHLGGPYGNSEPSWKVGSTYTYRFPNF
3. L12A01007| From 1 To 80 E-value: 1.99993e-41 Score: 159
DDMTMKPTPPPQYPLNLQGGGGGGSGDGFGFAVQGHQKVWTSDNGRHEIGLNGGYGQHLGGPYGNSEPSWKVGSTYTYRF
4. L13A020729 From 1 To 50 E-value: 8e-24 Score: 100
DDMTMKPTPPPQYPLNLQGGGGGGSGDGFGFAVQGHQKVWTSDNGRHEIG
5. L01A002945 From 7 To 82 E-value: 2e-19 Score: 86.3
ILPTPAPPNLPQLVGGGGGNRKDGFGVSVDAHQKVWTSDNGRHSIGVTPGYSQHLGGPYGNSRPDYRIGAGYSYNF

Reference
[1] Samakovlis C.,Hultmark D.,Hoffmann D.,Reichhart J.-M.,Wicker C.,
Title:Insect immunity. Characterization of a Drosophila cDNA encoding a novel member of the diptericin family of immune peptides.
Journal:J. Biol. Chem., 1990, 265, 22493-22498 [MEDLINE:91093098]
[2] Hoffmann D.,Zachary D.,Dimarcq J.-L.,Meister M.,Reichhart J.-M.,
Title:Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter.
Journal:EMBO J., 1992, 11, 1469-1477 [MEDLINE:92224885]
[3] Wang L.,Clark A.G.,
Title:Molecular population genetics of Drosophila immune system genes.
Journal:Genetics, 1997, 147, 713-724 [MEDLINE:97476321]
[4] Lemaitre B.,Abrams J.M.,Khush R.S.,Rodriguez A.,Leulier F.,
Title:The Drosophila caspase Dredd is required to resist Gram-negative bacterial infection.
Journal:EMBO Rep., 2000, 1, 353-358 [PubMed:11269502]
[5] Gocayne J.D.,Evans C.A.,Holt R.A.,Celniker S.E.,Adams M.D.,
Title:The genome sequence of Drosophila melanogaster.
Journal:Science, 2000, 287, 2185-2195 [MEDLINE:20196006]
[6] Champe M.,Yu C.,Brokstein P.,Carlson J.W.,Stapleton M.,
Title:A Drosophila full-length cDNA resource.
Journal:Genome Biol., 2002, 3, 0-0 [MEDLINE:22426066]
[7] Campbell K.S.,Matthews B.B.,Mungall C.J.,Crosby M.A.,Misra S.,
Title:Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
Journal:Genome Biol., 2002, 3, 0-0 [MEDLINE:22426069]