Record in detail

General Info

lamp_id:L01A000096
Name:TEMP_RANGU
FullName:Temporin-GH
Source:Rana guentheri
Mass:1440.8 Da
Sequence Length:13 aa
Isoelectric Point:7.55
Activity:Antibacterial
Sequence
FLPLLFGAISHLL
Function:Antimicrobial peptide. Active against the Gram-positive bacteria S.aureus FDA209P (MIC=44.3 ug/ml) and B.subtilis ATCC 6633 (MIC>64 ug/ml), but not active against the Gram-negative bacterium E.coli or the fungus C.albicans.

Cross-Linking

Cross-linking
1 Database:APD 586
2 Database:CAMP CAMPSQ86
3 Database:DBAASP 1587
4 Database:dbAMP dbAMP_02124
5 Database:DRAMP DRAMP01815
6 Database:SATPdb satpdb13989
7 Database:Uniprot P84858

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000096 From 1 To 13 E-value: 0.074 Score: 26.6
FLPLLFGAISHLL
2. L13A013506 From 1 To 12 E-value: 0.16 Score: 25.8
FLPLLFGAISHL
3. L13A024132 From 1 To 13 E-value: 1.3 Score: 22.7
FLPLLFGALSTLL
4. L13A023665 From 1 To 13 E-value: 1.3 Score: 22.7
FLPLLFGALSTLL
5. L13A012434 From 1 To 13 E-value: 3.2 Score: 21.2
FFPLLFGALSSLL

Structure

Domains

Structures

Activity

Antibacterial Activities
1 Target: S. aureus FDA209P MIC: 44.3 μg/ml (30.7468 μM)
2 Target: B.subtilis ATCC 6633 MIC: 64 μg/ml (44.4198 μM)
3 Target: S. aureus MIC: 44.3766 μg/ml (30.8 μM)

Toxicity

Toxicity

Reference

Reference
[1] Shaw C.,Zhang Y.,Thompson A.,McClean S.,Zhou J.,
Title:Purification and characterization of novel antimicrobial peptides from the skin secretion of Hylarana guentheri.
Journal:Peptides, 2006, 27, 3077-3084 [PubMed:16979798]

Comments

Comments