Record in detail

General Info

lamp_id:L01A000098
Name:BR1SE_RANSV
FullName:Brevinin-1SE
Source:Rana sevosa
Mass:2442 Da
Sequence Length:23 aa
Isoelectric Point:10.78
Activity:Antibacterial
Sequence
FLPLVRGAAKLIPSVVCAISKRC
Function:Mast cell degranulating peptide. Causes histamine release from rat peritoneal mast cells in vitro. Has antibacterial activity against the Gram-negative bacterium E.coli K12 and Gram-positive bacterium M.luteus NCT C2665.

Cross-Linking

Cross-linking
1 Database:CAMP CAMPSQ88
2 Database:dbAMP dbAMP_02134
3 Database:DRAMP DRAMP01945
4 Database:SATPdb satpdb16339
5 Database:Uniprot P85056

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000098 From 1 To 23 E-value: 0.0000001 Score: 46.6
FLPLVRGAAKLIPSVVCAISKRC
2. L02A001498 From 1 To 23 E-value: 0.000001 Score: 43.5
FLPLVRVAAKLIPSVVCAISKRC
3. L13A017291 From 1 To 23 E-value: 0.001 Score: 33.5
FLPVIAGAANFLPKLFCAISKKC
4. L13A024715 From 1 To 24 E-value: 0.002 Score: 33.1
FLPAVLRVAAKIVPSVVCAITKKC
5. L01A000447 From 1 To 24 E-value: 0.002 Score: 32.7
FLPVVAGLAAKVLPSIICAVTKKC

Structure

Domains
1 Name:Antimicrobial_frog_1 Interpro Link:IPR012520

Structures

Activity

Antibacterial Activities

Toxicity

Toxicity

Reference

Reference
[1] Flatt P.R.,O"Kane E.,McClean S.,Richter S.C.,Graham C.,
Title:Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.
Journal:Peptides, 2006, 27, 1313-1319 [PubMed:16386333]

Comments

Comments