Record in detail


General Info

  • lamp_id:L01A000099
  • Name:BR2GA_RANGU
  • FullName:Brevinin-2GHa
  • Source:Rana guentheri
  • Mass:3417 Da
  • Sequence Length:34 aa
  • Isoelectric Point:10.38
  • Activity:Antibacterial
  • Sequence
        GFSSLFKAGAKYLLKSVGKAGAQQLACKAANNCA
  • Function:Antimicrobial peptide. Active against the Gram-positive bacteria S.aureus FDA209P (MIC=14.9 ug/ml) and B.subtilis ATCC 6633 (MIC>64 ug/ml), but not active against the Gram-negative bacterium E.coli or the fungus C.albicans.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000099    From 1 To 34 E-value: 0.0000000000003 Score: 65.5
        GFSSLFKAGAKYLLKSVGKAGAQQLACKAANNCA
  • 2. L13A017513    From 1 To 37 E-value: 0.000001 Score: 43.9
        GIFSLFKAGAKFFGKNLLKEAGKAGAEHLACKAANQC
  • 3. L12A07243|    From 40 To 76 E-value: 0.000001 Score: 43.5
        GIFSLFKAGAKFFGKHLLKQAGKAGAEHLACKATNQC
  • 4. L13A010483    From 1 To 37 E-value: 0.000002 Score: 42.7
        GIFSLFKAGAKFFGKHLLKQAGKAGAEHLACKATNQC
  • 5. L12A07228|    From 43 To 76 E-value: 0.000006 Score: 41.2
        SLFKAGAKFFGKNLLKEAGKAGAAHLACKATNQC

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S. aureus FDA209P  MIC:  14.9 μg/ml  (4.36055 μM)  
  •   2  Target:  B.subtilis ATCC 6633  MIC:  64 μg/ml  (18.7299 μM)  
  •   3  Target:  S. aureus  MIC:  15.0348 μg/ml  (4.4 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Shaw C.,Zhang Y.,Thompson A.,McClean S.,Zhou J.,
  •   Title:Purification and characterization of novel antimicrobial peptides from the skin secretion of Hylarana guentheri.
  •   Journal:Peptides, 2006, 27, 3077-3084  [PubMed:16979798]

Comments

  •   Comments

  •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: