Record in detail

lamp_id:L01A000100
Name:BR2GB_RANGU
FullName:Brevinin-2GHb
Source:Rana guentheri
Mass:3083.6 Da
Sequence Length:30 aa
Isoelectric Point:9.6
Activity:Antibacterial
Sequence
GVITDALKGAAKTVAAELLRKAHCKLTNSC
Function:Antimicrobial peptide. Active against the Gram-positive bacteria S.aureus FDA209P (MIC=16.5 ug/ml) and B.subtilis ATCC 6633 (MIC>64 ug/ml), and the Gram-negative bacteria E.coli O111 (MIC=8.2 ug/ml) and E.coli ATCC 25922 (MIC=8.2 ug/ml). Not active against the fungus C.albicans.

Top similar AMPs on LAMP
1. L12A07325| From 43 To 72 E-value: 0.000000000005 Score: 61.6
GVITDALKGAAKTVAAELLRKAHCKLTNSC
2. L01A000100 From 1 To 30 E-value: 0.00000000001 Score: 60.5
GVITDALKGAAKTVAAELLRKAHCKLTNSC
3. L07APD0160 From 1 To 30 E-value: 0.0000000001 Score: 56.6
GVIIDTLKGAAKTVAAELLRKAHCKLTNSC
4. L01A003382 From 1 To 30 E-value: 0.0000004 Score: 45.4
GAIKDALKGAAKTVAVELLKKAQCKLEKTC
5. L12A07332| From 44 To 73 E-value: 0.00004 Score: 38.9
GILTDTLKGAAKNVAGVLLDKLKCKITGGC

Antibacterial Activities
1 Target: S. aureus FDA209P MIC: 16.5 μg/ml (5.35089 μM)
2 Target: B. subtilis ATCC 6633 MIC: 64 μg/ml (20.755 μM)
3 Target: E. coli O111 MIC: 8.2 μg/ml (2.65923 μM)
4 Target: E. coli ATCC 25922 MIC: 8.2 μg/ml (2.65923 μM)
5 Target: E. coli MIC: 8.32572 μg/ml (2.7 μM)
6 Target: S. aureus MIC: 16.6514 μg/ml (5.4 μM)

Reference
[1] Shaw C.,Zhang Y.,Thompson A.,McClean S.,Zhou J.,
Title:Purification and characterization of novel antimicrobial peptides from the skin secretion of Hylarana guentheri.
Journal:Peptides, 2006, 27, 3077-3084 [PubMed:16979798]