Record in detail


General Info

  • lamp_id:L01A000104
  • Name:CR119_LITGR
  • FullName:Caerin-1.19
  • Source:Litoria gracilenta
  • Mass:2651.2 Da
  • Sequence Length:25 aa
  • Isoelectric Point:10.51
  • Activity:Antibacterial
  • Sequence
        GLFKVLGSVAKHLLPHVAPIIAEKL
  • Function:Caerin-1.19 shows significant activity against Gram-positive organisms, but is less effective against Gram-negative organisms.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000104    From 1 To 25 E-value: 0.00000002 Score: 49.7
        GLFKVLGSVAKHLLPHVAPIIAEKL
  • 2. L01A000529    From 1 To 25 E-value: 0.00000003 Score: 48.9
        GLFKVLGSVAKHLLPHVAPVIAEKL
  • 3. L13A022636    From 1 To 24 E-value: 0.00000005 Score: 48.1
        GLFKVLGSVAKHLLPHVAPIIAEK
  • 4. L01A000102    From 1 To 25 E-value: 0.00000006 Score: 48.1
        GLFSVLGSVAKHLLPHVAPIIAEKL
  • 5. L01A002352    From 1 To 24 E-value: 0.00000008 Score: 47.8
        GLFKVLGSVAKHLLPHVAPVIAEK

Structure

  •   Domains
  •   1  Name:Caerin_1    Interpro Link:IPR010000
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Bacillus cereus  MIC:  50 μg/ml  (18.8594 μM)  
  •   2  Target:  Leuconostoc lactis  MIC:  3 μg/ml  (1.13156 μM)  
  •   3  Target:  Listeria innocua  MIC:  12 μg/ml  (4.52625 μM)  
  •   4  Target:  Micrococcus luteus  MIC:  25 μg/ml  (9.42969 μM)  
  •   5  Target:  Staphylococcus aureus Strain ATCC 25923  MIC:  12 μg/ml  (4.52625 μM)  
  •   6  Target:  Staphylococcus aureus Strain ATCC 29213  MIC:  12 μg/ml  (4.52625 μM)  
  •   7  Target:  Staphylococcus epidermidis  MIC:  12 μg/ml  (4.52625 μM)  
  •   8  Target:  Streptococcus uberis  MIC:  25 μg/ml  (9.42969 μM)  
  •   9  Target:  Pasteurella multocida  MIC:  50 μg/ml  (18.8594 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Doyle J.R.,Bowie J.H.,Bilusich D.,Brinkworth C.S.,Maclean M.J.,
  •   Title:New caerin antibiotic peptides from the skin secretion of the dainty green tree frog Litoria gracilenta. Identification using positive and negative ion electrospray mass spectrometry.
  •   Journal:Toxicon, 2006, 47, 664-675  [PubMed:16554081]

Comments

  •   Comments

  •     No comments found on LAMP database



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