Record in detail

lamp_id:L01A000104
Name:CR119_LITGR
FullName:Caerin-1.19
Source:Litoria gracilenta
Mass:2651.2 Da
Sequence Length:25 aa
Isoelectric Point:10.51
Activity:Antibacterial
Sequence
GLFKVLGSVAKHLLPHVAPIIAEKL
Function:Caerin-1.19 shows significant activity against Gram-positive organisms, but is less effective against Gram-negative organisms.

Top similar AMPs on LAMP
1. L01A000104 From 1 To 25 E-value: 0.00000002 Score: 49.7
GLFKVLGSVAKHLLPHVAPIIAEKL
2. L01A000529 From 1 To 25 E-value: 0.00000003 Score: 48.9
GLFKVLGSVAKHLLPHVAPVIAEKL
3. L13A022636 From 1 To 24 E-value: 0.00000005 Score: 48.1
GLFKVLGSVAKHLLPHVAPIIAEK
4. L01A000102 From 1 To 25 E-value: 0.00000006 Score: 48.1
GLFSVLGSVAKHLLPHVAPIIAEKL
5. L01A002352 From 1 To 24 E-value: 0.00000008 Score: 47.8
GLFKVLGSVAKHLLPHVAPVIAEK

Antibacterial Activities
1 Target: Bacillus cereus MIC: 50 μg/ml (18.8594 μM)
2 Target: Leuconostoc lactis MIC: 3 μg/ml (1.13156 μM)
3 Target: Listeria innocua MIC: 12 μg/ml (4.52625 μM)
4 Target: Micrococcus luteus MIC: 25 μg/ml (9.42969 μM)
5 Target: Staphylococcus aureus Strain ATCC 25923 MIC: 12 μg/ml (4.52625 μM)
6 Target: Staphylococcus aureus Strain ATCC 29213 MIC: 12 μg/ml (4.52625 μM)
7 Target: Staphylococcus epidermidis MIC: 12 μg/ml (4.52625 μM)
8 Target: Streptococcus uberis MIC: 25 μg/ml (9.42969 μM)
9 Target: Pasteurella multocida MIC: 50 μg/ml (18.8594 μM)

Reference
[1] Doyle J.R.,Bowie J.H.,Bilusich D.,Brinkworth C.S.,Maclean M.J.,
Title:New caerin antibiotic peptides from the skin secretion of the dainty green tree frog Litoria gracilenta. Identification using positive and negative ion electrospray mass spectrometry.
Journal:Toxicon, 2006, 47, 664-675 [PubMed:16554081]