Record in detail


General Info

  • lamp_id:L01A000108
  • Name:ES2SE_RANSV
  • FullName:Esculentin-2SE
  • Source:Rana sevosa
  • Mass:3839.7 Da
  • Sequence Length:37 aa
  • Isoelectric Point:10.41
  • Activity:Antibacterial
  • Sequence
        GFFSLIKGVAKIATKGLAKNLGKMGLDLVGCKISKEC
  • Function:Mast cell degranulating peptide. Causes histamine release from rat peritoneal mast cells in vitro. Has antibacterial activity against the Gram-negative bacterium E.coli K12 and Gram-positive bacterium M.luteus NCT C2665.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000108    From 1 To 37 E-value: 0.000000000000004 Score: 71.6
        GFFSLIKGVAKIATKGLAKNLGKMGLDLVGCKISKEC
  • 2. L02A000651    From 1 To 37 E-value: 0.000000000008 Score: 60.8
        GLFSILKGVGKIALKGLAKNMGKMGLDLVSCKISKEC
  • 3. L01A003315    From 1 To 37 E-value: 0.00000000002 Score: 59.7
        GLFSILKGVGKIAIKGLGKNLGKMGLDLVSCKISKEC
  • 4. L12A08200|    From 4 To 40 E-value: 0.000000003 Score: 52
        GFSSIFRGVAKFASKGLGKDLAKLGVDLVACKISKQC
  • 5. L102654000    From 1 To 37 E-value: 0.000000003 Score: 52
        GFSSIFRGVAKFASKGLGKDLAKLGVDLVACKISKQC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Flatt P.R.,O"Kane E.,McClean S.,Richter S.C.,Graham C.,
  •   Title:Histamine-releasing and antimicrobial peptides from the skin secretions of the dusky gopher frog, Rana sevosa.
  •   Journal:Peptides, 2006, 27, 1313-1319  [PubMed:16386333]

Comments

  •   Comments

    •     No comments found on LAMP database



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