Record in detail

lamp_id:L01A000121
Name:MAGA_XENLA
FullName:Magainins
Source:Xenopus laevis
Mass:2409.9 Da
Sequence Length:23 aa
Isoelectric Point:10.8
Activity:Antibacterial
Sequence
GIGKFLHSAGKFGKAFVGEIMKS
Function:Antimicrobial peptides that inhibit the growth of numerous species of bacteria and fungi and induce osmotic lysis of protozoa. Magainins are membrane lytic agents.

Top similar AMPs on LAMP
1. L01A000121 From 1 To 23 E-value: 0.0000002 Score: 45.8
GIGKFLHSAGKFGKAFVGEIMKS
2. L102718000 From 1 To 23 E-value: 0.0000004 Score: 45.1
GIGKFLHSAGKFGKAFIGEIMKS
3. L102715000 From 1 To 23 E-value: 0.0000008 Score: 44.3
GIGKFLHSAGKFGKAFLGEVMKS
4. L01A001962 From 1 To 22 E-value: 0.0000008 Score: 43.9
GIGKFLHSAGKFGKAFVGEIMK
5. L11A005611 From 5 To 27 E-value: 0.000003 Score: 42
GIGKFLHSAKKFGKAFVGEIMNS

Reference
[1] Zasloff M.
Title:Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.
Journal:Proc. Natl. Acad. Sci. U.S.A., 1987, 84, 5449-5453 [MEDLINE:87261003]
[2] Giovannini M.G.,Nutkins J.C.,Williams D.H.,Poulter L.,Terry A.S.,
Title:The cDNA sequence coding for prepro-PGS (prepro-magainins) and aspects of the processing of this prepro-polypeptide.
Journal:J. Biol. Chem., 1988, 263, 5745-5751 [MEDLINE:88186892]
[3] Turner K.,Tomassini N.,Brasseur M.M.,Bevins C.L.,Moore K.S.,
Title:Antimicrobial peptides in the stomach of Xenopus laevis.
Journal:J. Biol. Chem., 1991, 266, 19851-19857 [MEDLINE:92011794]
[4] Opella S.J.,Zasloff M.,Bechinger B.,
Title:Structure and orientation of the antibiotic peptide magainin in membranes by solid-state nuclear magnetic resonance spectroscopy.
Journal:Protein Sci., 1993, 2, 2077-2084 [MEDLINE:94129391]