Record in detail


General Info

  • lamp_id:L01A000130
  • Name:PPM1_LIMPO
  • FullName:Polyphemusin-1
  • Source:Limulus polyphemus
  • Mass:2458.9 Da
  • Sequence Length:18 aa
  • Isoelectric Point:10.64
  • Activity:Antibacterial, Antifungal
  • Sequence
        RRWCFRVCYRGFCYRKCR
  • Function:Significantly inhibits the growth of Gram-negative and Gram-positive bacteria.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A10746|    From 1 To 18 E-value: 0.00006 Score: 37.4
        RRWCFRVCYRGFCYRKCR
  • 2. L01A000130    From 1 To 18 E-value: 0.00006 Score: 37.4
        RRWCFRVCYRGFCYRKCR
  • 3. L12A07972|    From 24 To 40 E-value: 0.00006 Score: 37.4
        RWCFRVCYRGICYRKCR
  • 4. L03A000352    From 25 To 41 E-value: 0.00006 Score: 37.4
        RWCFRVCYRGICYRKCR
  • 5. L01A000131    From 1 To 18 E-value: 0.00009 Score: 37
        RRWCFRVCYKGFCYRKCR

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Iwanaga S.,Yoshikawa K.,Yonega T.,Tokunaga F.,Miyata T.,
  •   Title:Antimicrobial peptides, isolated from horseshoe crab hemocytes, tachyplesin II, and polyphemusins I and II: chemical structures and biological activity.
  •   Journal:J. Biochem., 1989, 106, 663-668  [MEDLINE:90110066]
  •   [2]  Hancock R.E.,Rozek A.,Powers J.P.,
  •   Title:Structure-activity relationships for the beta-hairpin cationic antimicrobial peptide polyphemusin I.
  •   Journal:Biochim. Biophys. Acta, 2004, 1698, 239-250  [PubMed:15134657]

Comments

  •   Comments

    •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: