Record in detail

General Info

lamp_id:L01A000133
Name:TIN2_HOPTI
FullName:Tigerinin-2
Source:Hoplobatrachus tigerinus
Mass:1368.7 Da
Sequence Length:12 aa
Isoelectric Point:8.24
Activity:Antibacterial, Antifungal
Sequence
RVCFAIPLPICH
Function:Antibacterial activity against B.subtilis, E.coli, S.aureus, M.luteus and P.putida. Antifungal activity against S.cerevisiae.

Cross-Linking

Cross-linking
1 Database:APD 304
2 Database:CAMP CAMPSQ121
3 Database:DBAASP 652
4 Database:dbAMP dbAMP_10818
5 Database:DRAMP DRAMP01351
6 Database:SATPdb satpdb11528
7 Database:Uniprot P82652
8 Database:AMD TIN2_HOPTI

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000133 From 1 To 12 E-value: 0.026 Score: 28.1
RVCFAIPLPICH
2. L01A000134 From 1 To 12 E-value: 0.13 Score: 25.8
RVCYAIPLPICY
3. L10C7ENH50 From 1 To 12 E-value: 0.16 Score: 25.4
RVCSAIPLPICH
4. L10C7ENH60 From 1 To 12 E-value: 0.16 Score: 25.4
RVCMAIPLPLCH
5. L11A004429 From 1 To 12 E-value: 0.19 Score: 25.4
RVCKAIPLPICH

Structure

Domains

Structures

Activity

Antibacterial Activities
1 Target: B. subtilis MIC: 20 μg/ml (14.6124 μM)
2 Target: E. coli MIC: 50 μg/ml (36.531 μM)
3 Target: S. aureus ATCC 8530 MIC: 40 μg/ml (29.2248 μM)
4 Target: M. luteus MT 166 MIC: 20 μg/ml (14.6124 μM)
5 Target: P. putida NCIM 2102 MIC: 50 μg/ml (36.531 μM)
6 Target: S. cerevisiae ATCC 8530 MIC: 100 μg/ml (73.062 μM)
7 Target: E. coli MIC: 49.9576 μg/ml (36.5 μM)
8 Target: S. aureus MIC: 39.6923 μg/ml (29 μM)

Toxicity

Toxicity

Reference

Reference
[1] Devi A.S.,Raju N.P.,Vairamani M.,Jaganadham M.V.,Purna Sai K.,
Title:Tigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
Journal:J. Biol. Chem., 2001, 276, 2701-2707 [PubMed:11031261]

Comments

Comments