Record in detail

General Info

lamp_id:L01A000134
Name:TIN3_HOPTI
FullName:Tigerinin-3
Source:Hoplobatrachus tigerinus
Mass:1410.7 Da
Sequence Length:12 aa
Isoelectric Point:8.22
Activity:Antibacterial, Antifungal
Sequence
RVCYAIPLPICY
Function:Antibacterial activity against B.subtilis, E.coli, S.aureus, M.luteus and P.putida. Antifungal activity against S.cerevisiae.

Cross-Linking

Cross-linking
1 Database:APD 305
2 Database:CAMP CAMPSQ122
3 Database:DBAASP 657
4 Database:dbAMP dbAMP_10826
5 Database:DRAMP DRAMP01352
6 Database:SATPdb satpdb20210
7 Database:Uniprot P82653
8 Database:AMD TIN3_HOPTI

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000134 From 1 To 12 E-value: 0.039 Score: 27.7
RVCYAIPLPICY
2. L01A000133 From 1 To 12 E-value: 0.13 Score: 25.8
RVCFAIPLPICH
3. L01A000135 From 1 To 11 E-value: 0.16 Score: 25.4
RVCYAIPLPIC
4. L10C7ENH50 From 1 To 12 E-value: 0.34 Score: 24.3
RVCSAIPLPICH
5. L11A004429 From 1 To 12 E-value: 0.35 Score: 24.3
RVCKAIPLPICH

Structure

Domains

Structures

Activity

Antibacterial Activities
1 Target: B. subtilis MIC: 30 μg/ml (21.266 μM)
2 Target: E. coli MIC: 40 μg/ml (28.3547 μM)
3 Target: S. aureus ATCC 8530 MIC: 30 μg/ml (21.266 μM)
4 Target: M. luteus MT 166 MIC: 30 μg/ml (21.266 μM)
5 Target: P. putida NCIM 2102 MIC: 40 μg/ml (28.3547 μM)
6 Target: S. cerevisiae ATCC 8530 MIC: 80 μg/ml (56.7094 μM)
7 Target: E. coli MIC: 39.4996 μg/ml (28 μM)
8 Target: S. aureus MIC: 29.6247 μg/ml (21 μM)

Toxicity

Toxicity

Reference

Reference
[1] Devi A.S.,Raju N.P.,Vairamani M.,Jaganadham M.V.,Purna Sai K.,
Title:Tigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
Journal:J. Biol. Chem., 2001, 276, 2701-2707 [PubMed:11031261]

Comments

Comments