Record in detail

General Info

lamp_id:L01A000135
Name:TIN4_HOPTI
FullName:Tigerinin-4
Source:Hoplobatrachus tigerinus
Mass:1247.6 Da
Sequence Length:11 aa
Isoelectric Point:8.22
Activity:Antibacterial, Antifungal
Sequence
RVCYAIPLPIC
Function:Antibacterial activity against B.subtilis, E.coli, S.aureus, M.luteus and P.putida. Antifungal activity against S.cerevisiae.

Cross-Linking

Cross-linking
1 Database:APD 306
2 Database:CAMP CAMPSQ123
3 Database:DBAASP 658
4 Database:dbAMP dbAMP_10825
5 Database:DRAMP DRAMP01353
6 Database:SATPdb satpdb11870
7 Database:Uniprot P82654
8 Database:AMD TIN4_HOPTI

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000135 From 1 To 11 E-value: 0.14 Score: 25.4
RVCYAIPLPIC
2. L01A000134 From 1 To 11 E-value: 0.15 Score: 25.4
RVCYAIPLPIC
3. L01A000133 From 1 To 11 E-value: 0.26 Score: 24.6
RVCFAIPLPIC
4. L11A004431 From 1 To 11 E-value: 0.71 Score: 23.1
RVCSAIPLPIC
5. L10C7ENH50 From 1 To 11 E-value: 0.78 Score: 23.1
RVCSAIPLPIC

Structure

Domains

Structures

Activity

Antibacterial Activities
1 Target: E. coli MIC: 60 μg/ml (48.0923 μM)
2 Target: S. aureus ATCC 8530 MIC: 50 μg/ml (40.077 μM)
3 Target: P. putida NCIM 2102 MIC: 60 μg/ml (48.0923 μM)
4 Target: S. cerevisiae ATCC 8530 MIC: 100 μg/ml (80.1539 μM)
5 Target: E. coli MIC: 59.8848 μg/ml (48 μM)
6 Target: S. aureus MIC: 49.904 μg/ml (40 μM)

Toxicity

Toxicity

Reference

Reference
[1] Devi A.S.,Raju N.P.,Vairamani M.,Jaganadham M.V.,Purna Sai K.,
Title:Tigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina.
Journal:J. Biol. Chem., 2001, 276, 2701-2707 [PubMed:11031261]

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Comments