Record in detail


General Info

  • lamp_id:L01A000137
  • Name:SRX1A_SARPE
  • FullName:Sarcotoxin-1A
  • Source:Sarcophaga peregrina
  • Mass:4156.8 Da
  • Sequence Length:39 aa
  • Isoelectric Point:11.72
  • Activity:Antibacterial
  • Sequence
        GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR
  • Function:Sarcotoxins, which are potent bactericidal proteins, are produced in response to injury. They are cytotoxic to both Gram-positive and Gram-negative bacteria.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000228    From 24 To 62 E-value: 3e-17 Score: 79
        GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR
  • 2. L12A08769|    From 24 To 62 E-value: 3e-17 Score: 79
        GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR
  • 3. L03A000209    From 24 To 62 E-value: 3e-17 Score: 79
        GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR
  • 4. L01A002411    From 17 To 55 E-value: 5e-17 Score: 78.2
        GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR
  • 5. L12A08777|    From 24 To 62 E-value: 8e-17 Score: 77.4
        GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAK

Structure

  •   Domains
  •   1  Name:Cecropin    Interpro Link:IPR000875
  •   2  Name:Cecropin_diptera    Interpro Link:IPR020400
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Natori S.,Okada M.,
  •   Title:Primary structure of sarcotoxin I, an antibacterial protein induced in the hemolymph of Sarcophaga peregrina (flesh fly) larvae.
  •   Journal:J. Biol. Chem., 1985, 260, 7174-7177  [MEDLINE:85207747]
  •   [2]  Nakajima Y.,Ming Q.X.,Takahashi H.,Okada M.,Matsumoto N.,
  •   Title:Molecular cloning of a cDNA and assignment of the C-terminal of sarcotoxin IA, a potent antibacterial protein of Sarcophaga peregrina.
  •   Journal:Biochem. J., 1986, 239, 717-722  [MEDLINE:87156539]
  •   [3]  Shimada I.,Arata Y.,Natori S.,Nakajima Y.,Iwai H.,
  •   Title:Solution conformation of an antibacterial peptide, sarcotoxin IA, as determined by 1H-NMR.
  •   Journal:Eur. J. Biochem., 1993, 217, 639-644  [MEDLINE:94039100]

Comments

  •   Comments

  •     No comments found on LAMP database



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