Record in detail
General Info
- lamp_id:L01A000137
- Name:SRX1A_SARPE
- FullName:Sarcotoxin-1A
- Source:Sarcophaga peregrina
- Mass:4156.8 Da
- Sequence Length:39 aa
- Isoelectric Point:11.72
- Activity:Antibacterial
- Sequence
GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR - Function:Sarcotoxins, which are potent bactericidal proteins, are produced in response to injury. They are cytotoxic to both Gram-positive and Gram-negative bacteria.
Cross-Linking
- Cross-linking
- 1 Database:APD 230
- 2 Database:CAMP CAMPSQ125
- 3 Database:DBAASP 1855
- 4 Database:dbAMP dbAMP_04369
- 5 Database:DRAMP DRAMP03089
- 6 Database:SATPdb satpdb10156
- 7 Database:Uniprot P08375
- 8 Database:RAP RAPD0110
- 9 Database:RAP RAPD0111
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000228 From 24 To 62 E-value: 3e-17 Score: 79
GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR - 2. L12A08769| From 24 To 62 E-value: 3e-17 Score: 79
GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR - 3. L03A000209 From 24 To 62 E-value: 3e-17 Score: 79
GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR - 4. L01A002411 From 17 To 55 E-value: 5e-17 Score: 78.2
GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR - 5. L12A08777| From 24 To 62 E-value: 8e-17 Score: 77.4
GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAK
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Natori S.,Okada M.,
- Title:Primary structure of sarcotoxin I, an antibacterial protein induced in the hemolymph of Sarcophaga peregrina (flesh fly) larvae.
- Journal:J. Biol. Chem., 1985, 260, 7174-7177 [MEDLINE:85207747]
- [2] Nakajima Y.,Ming Q.X.,Takahashi H.,Okada M.,Matsumoto N.,
- Title:Molecular cloning of a cDNA and assignment of the C-terminal of sarcotoxin IA, a potent antibacterial protein of Sarcophaga peregrina.
- Journal:Biochem. J., 1986, 239, 717-722 [MEDLINE:87156539]
- [3] Shimada I.,Arata Y.,Natori S.,Nakajima Y.,Iwai H.,
- Title:Solution conformation of an antibacterial peptide, sarcotoxin IA, as determined by 1H-NMR.
- Journal:Eur. J. Biochem., 1993, 217, 639-644 [MEDLINE:94039100]
Comments
- Comments
No comments found on LAMP database