Record in detail


General Info

  • lamp_id:L01A000141
  • Name:DEFB6_BOVIN
  • FullName:Beta-defensin 6
  • Source:Bos taurus
  • Mass:4838.7 Da
  • Sequence Length:42 aa
  • Isoelectric Point:11.2
  • Activity:Antibacterial
  • Sequence
        QGVRNHVTCRIYGGFCVPIRCPGRTRQIGTCFGRPVKCCRRW
  • Function:Has bactericidal activity. Active against E.coli ML35 and S.aureus 502A.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000141    From 1 To 42 E-value: 3e-19 Score: 85.1
        QGVRNHVTCRIYGGFCVPIRCPGRTRQIGTCFGRPVKCCRRW
  • 2. L01A000366    From 1 To 42 E-value: 6e-19 Score: 84.3
        EGVRNHVTCRIYGGFCVPIRCPGRTRQIGTCFGRPVKCCRRW
  • 3. L03A000069    From 16 To 57 E-value: 0.000000000000001 Score: 73.6
        QGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
  • 4. L12A02363|    From 3 To 44 E-value: 0.000000000000003 Score: 72
        QGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
  • 5. L02A000038    From 1 To 42 E-value: 0.000000000000004 Score: 72
        QGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW

Structure

  •   Domains
  •   1  Name:Defensin_beta-typ    Interpro Link:IPR001855
  •   2  Name:Defensin_beta/neutrophil    Interpro Link:IPR006080
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Novotny M.J.,McGuire P.A.,Morris W.L.,Tang Y.-Q.,Selsted M.E.,
  •   Title:Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
  •   Journal:J. Biol. Chem., 1993, 268, 6641-6648  [MEDLINE:93203264]

Comments

  •   Comments

    •     No comments found on LAMP database



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