Record in detail


General Info

  • lamp_id:L01A000143
  • Name:DEF2_CAVPO
  • FullName:Neutrophil cationic peptide 2
  • Source:Cavia porcellus
  • Mass:3838.5 Da
  • Sequence Length:31 aa
  • Isoelectric Point:9.62
  • Activity:Antibacterial, Antifungal, Antiviral
  • Sequence
        RRCICTTRTCRFPYRRLGTCLFQNRVYTFCC
  • Function:Has antibiotic, anti-fungi and antiviral activity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A09267|    From 63 To 93 E-value: 0.0000000000002 Score: 66.6
        RRCICTTRTCRFPYRRLGTCLFQNRVYTFCC
  • 2. L12A09265|    From 63 To 93 E-value: 0.0000000000003 Score: 65.9
        RRCICTTRTCRFPYRRLGTCIFQNRVYTFCC
  • 3. L12A09266|    From 63 To 93 E-value: 0.0000000000003 Score: 65.5
        RRCICTTRTCRFPYRRLGTCIFQNRVYTFCC
  • 4. L01A000143    From 1 To 31 E-value: 0.000000000005 Score: 61.6
        RRCICTTRTCRFPYRRLGTCLFQNRVYTFCC
  • 5. L01A003255    From 1 To 31 E-value: 0.000000000008 Score: 60.8
        RRCICTTRTCRFPYRRLGTCIFQNRVYTFCC

Structure

  •   Domains
  •   1  Name:Alpha-defensin    Interpro Link:IPR016327
  •   2  Name:Defensin_beta/neutrophil    Interpro Link:IPR006080
  •   3  Name:Defensin_propep    Interpro Link:IPR002366
  •   4  Name:Mammalian_defensins    Interpro Link:IPR006081
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Yamashita T.,Iwabuchi K.,Someya A.,Nagaoka I.,
  •   Title:Characterization of cDNA clones encoding guinea pig neutrophil cationic peptides.
  •   Journal:FEBS Lett., 1991, 280, 287-291  [MEDLINE:91192152]
  •   [2]  Yamashita T.,Iwabuchi K.,Someya A.,Nagaoka I.,
  •   Title:Structure of the guinea pig neutrophil cationic peptide gene.
  •   Journal:FEBS Lett., 1992, 303, 31-35  [MEDLINE:92275076]
  •   [3]  Yamashita T.,Nonoguchi A.,Nagaoka I.,
  •   Title:Cloning and characterization of the guinea pig neutrophil cationic peptide-1 and -2 genes.
  •   Journal:DNA Seq., 1993, 4, 123-128  [MEDLINE:94227245]

Comments

  •   Comments

  •     No comments found on LAMP database



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