Record in detail
General Info
- lamp_id:L01A000144
- Name:TAC1_TACTR
- FullName:Tachyplesin-1
- Source:Tachypleus tridentatus
- Mass:2268.7 Da
- Sequence Length:17 aa
- Isoelectric Point:10.07
- Activity:Antibacterial,Anticancer
- Sequence
KWCFRVCYRGICYRRCR - Function:Significantly inhibits the growth of Gram-negative and Gram-positive bacteria.
Cross-Linking
- Cross-linking
- 1 Database:APD 214
- 2 Database:CAMP CAMPSQ1258
- 3 Database:DBAASP 2229
- 4 Database:dbAMP dbAMP_05478
- 5 Database:DRAMP DRAMP02926
- 6 Database:SATPdb satpdb16986
- 7 Database:Uniprot P14213
- 8 Database:AMD TAC1_TACGI
- 9 Database:RAP RAPD0017
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000153 From 24 To 40 E-value: 0.00001 Score: 40
KWCFRVCYRGICYRRCR - 2. L12A07972| From 24 To 40 E-value: 0.00009 Score: 37
RWCFRVCYRGICYRKCR - 3. L03A000352 From 25 To 41 E-value: 0.00009 Score: 37
RWCFRVCYRGICYRKCR - 4. L12A05479| From 1 To 17 E-value: 0.0001 Score: 36.2
KWCFRVCYRGICYRRCR - 5. L01A000144 From 1 To 17 E-value: 0.0001 Score: 36.2
KWCFRVCYRGICYRRCR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Muta T.,Tokunaga F.,Miyata T.,Furunaka H.,Nakamura T.,
- Title:Tachyplesin, a class of antimicrobial peptide from the hemocytes of the horseshoe crab (Tachypleus tridentatus). Isolation and chemical structure.
- Journal:J. Biol. Chem., 1988, 263, 16709-16713 [MEDLINE:89034158]
- [2] Tokunaga F.,Yoshikawa K.,Miyata T.,Yoneya T.,Kawano K.,
- Title:Antimicrobial peptide, tachyplesin I, isolated from hemocytes of the horseshoe crab (Tachypleus tridentatus). NMR determination of the beta-sheet structure.
- Journal:J. Biol. Chem., 1990, 265, 15365-15367 [MEDLINE:90368729]
- [3] Iwanaga S.,Tokunaga F.,Toh Y.,Muta T.,Shigenaga T.,
- Title:Antimicrobial tachyplesin peptide precursor. cDNA cloning and cellular localization in the horseshoe crab (Tachypleus tridentatus).
- Journal:J. Biol. Chem., 1990, 265, 21350-21354 [MEDLINE:91065956]
- [4] Funakoshi S.,Otaka A.,Masuda M.,Kuroda M.,Tamamura H.,
- Title:A comparative study of the solution structures of tachyplesin I and a novel anti-HIV synthetic peptide, T22 ([Tyr5,12, Lys7]-polyphemusin II), determined by nuclear magnetic resonance.
- Journal:Biochim. Biophys. Acta, 1993, 1163, 209-216 [MEDLINE:93257488]
- [5] Muta T.,Seki N.,Kawasaki S.,Takayenoki Y.,Shigenaga T.,
- Title:Separation of large and small granules from horseshoe crab (Tachypleus tridentatus) hemocytes and characterization of their components.
- Journal:J. Biochem., 1993, 114, 307-316 [MEDLINE:94110249]
Comments
- Comments
No comments found on LAMP database