Record in detail
General Info
- lamp_id:L01A000180
- Name:PROP2_GALME
- FullName:Proline-rich antimicrobial peptide 2
- Source:Galleria mellonella
- Mass:4931.7 Da
- Sequence Length:42 aa
- Isoelectric Point:10.42
- Activity:Antibacterial
- Sequence
EIRLPEPFRFPSPTVPKPIDIDPILPHPWSPRQTYPIIARRS - Function:Antimicrobial protein. Has antibacterial activity against the Gram-positive bacterium M.luteus (MIC=8.6 uM). Lacks antibacterial activity against the Gram-positive bacteria B.circulans, L.monocytogenes, S.aureus, and S.lutea, and the Gram-negative bacteria E.coli D31, E.coli ATCC 25922, and S.typhimurium. Lacks antifungal activity against S.cerevisiae, P.pastoris, Z.marxianus, C.albicans, C.fructus, C.wickerhamii, A.niger, F.oxysporum, and T.harizianum.
Cross-Linking
- Cross-linking
- 1 Database:APD 750
- 2 Database:CAMP CAMPSQ166
- 3 Database:DBAASP 1215
- 4 Database:dbAMP dbAMP_01407
- 5 Database:DRAMP DRAMP03526
- 6 Database:SATPdb satpdb18342
- 7 Database:Uniprot P85212
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000180 From 1 To 42 E-value: 3e-18 Score: 82
EIRLPEPFRFPSPTVPKPIDIDPILPHPWSPRQTYPIIARRS
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: M. luteus MIC: 29.59 μg/ml (5.99996 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Jakubowicz T.,Suder P.,Zdybicka-Barabas A.,Mak P.,Cytrynska M.,
- Title:Purification and characterization of eight peptides from Galleria mellonella immune hemolymph.
- Journal:Peptides, 2007, 28, 533-546 [PubMed:17194500]
Comments
- Comments
No comments found on LAMP database