Record in detail


General Info

  • lamp_id:L01A000192
  • Name:MASTC_VESMG
  • FullName:Mastoparan-like peptide 12c
  • Source:Vespa magnifica
  • Mass:1536.9 Da
  • Sequence Length:15 aa
  • Isoelectric Point:11.1
  • Activity:Antibacterial, Antifungal
  • Sequence
        INLKAIAALAKKLLG
  • Function:Shows mast cell degranulation and antimicrobial activities against the Gram-negative bacteria E.coli ATCC 25922 (MIC=6.0 ug/ml), the Gram-positive bacteria S.aureus ATCC 2592 (MIC=3.0 ug/ml) and the fungus C.albicans ATCC 2002 (MIC=12 ug/ml).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A09278|    From 26 To 40 E-value: 0.021 Score: 28.9
        INLKAIAALAKKLLG
  • 2. L01A000192    From 1 To 15 E-value: 0.042 Score: 27.7
        INLKAIAALAKKLLG
  • 3. L02A000448    From 1 To 14 E-value: 0.22 Score: 25.4
        INLKAIAALAKKLL
  • 4. L01A000193    From 1 To 14 E-value: 0.31 Score: 25
        INLKAIAAMAKKLL
  • 5. L11A006384    From 1 To 14 E-value: 0.4 Score: 24.6
        INLKAIAALAKKLF

Structure

  •   Domains
  •   1  Name:Mastoparan    Interpro Link:IPR013213
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli ATCC 25922  MIC:  6 μg/ml  (3.90396 μM)  
  •   2  Target:  S. aureus ATCC 2592  MIC:  3 μg/ml  (1.95198 μM)  
  •   3  Target:  C. albicans ATCC 2002  MIC:  12 μg/ml  (7.80792 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lai R.,Li J.,Yu H.,Yang H.,Xu X.,
  •   Title:The mastoparanogen from wasp.
  •   Journal:Peptides, 2006, 27, 3053-3057  [PubMed:17046111]

Comments

  •   Comments

    •     No comments found on LAMP database



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