Record in detail

General Info

lamp_id:L01A000193
Name:MASTD_VESMG
FullName:Mastoparan-like peptide 12d
Source:Vespa magnifica
Mass:1497.9 Da
Sequence Length:14 aa
Isoelectric Point:11.1
Activity:Antibacterial, Antifungal
Sequence
INLKAIAAMAKKLL
Function:Shows mast cell degranulation and antimicrobial activities against the Gram-negative bacteria E.coli ATCC 25922 (MIC=3.0 ug/ml), the Gram-positive bacteria S.aureus ATCC 2592 (MIC=1.5 ug/ml) and the fungus C.albicans ATCC 2002 (MIC=12.0 ug/ml).

Cross-Linking

Cross-linking
1 Database:CAMP CAMPSQ176
2 Database:DBAASP 1641
3 Database:dbAMP dbAMP_04789
4 Database:DRAMP DRAMP03036
5 Database:SATPdb satpdb18301
6 Database:Uniprot P0C5G7

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000193 From 1 To 14 E-value: 0.12 Score: 26.2
INLKAIAAMAKKLL
2. L12A09278| From 26 To 39 E-value: 0.18 Score: 25.8
INLKAIAALAKKLL
3. L13A011272 From 1 To 13 E-value: 0.29 Score: 25
INLKAIAAMAKKL
4. L01A000192 From 1 To 14 E-value: 0.29 Score: 25
INLKAIAALAKKLL
5. L02A000448 From 1 To 14 E-value: 0.31 Score: 24.6
INLKAIAALAKKLL

Structure

Domains
1 Name:Mastoparan Interpro Link:IPR013213

Structures

Activity

Antibacterial Activities
1 Target: E. coli ATCC 25922 MIC: 3 μg/ml (2.0028 μM)
2 Target: S. aureus ATCC 2592 MIC: 1.5 μg/ml (1.0014 μM)
3 Target: C. albicans ATCC 2002 MIC: 12 μg/ml (8.01122 μM)

Toxicity

Toxicity

Reference

Reference
[1] Lai R.,Li J.,Yu H.,Yang H.,Xu X.,
Title:The mastoparanogen from wasp.
Journal:Peptides, 2006, 27, 3053-3057 [PubMed:17046111]

Comments

Comments