Record in detail


General Info

  • lamp_id:L01A000205
  • Name:B2DYD_RANDY
  • FullName:Brevinin-2DYd
  • Source:Rana dybowskii
  • Mass:3318 Da
  • Sequence Length:33 aa
  • Isoelectric Point:9.55
  • Activity:Antibacterial
  • Sequence
        GIFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC
  • Function:Antimicrobial peptide. A mixture of Brevinin-2DYc/2DYd is active against the Gram-positive bacterium S.aureus (MIC=15 uM) and the Gram-negative bacterium E.coli (MIC=15 uM).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000205    From 1 To 33 E-value: 0.000000000002 Score: 62.8
        GIFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC
  • 2. L01A002730    From 1 To 33 E-value: 0.000000000004 Score: 62
        GLFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC
  • 3. L01A000204    From 1 To 33 E-value: 0.000000000009 Score: 60.8
        GLFDVVKGVLKGAGKNVAGSLLEQLKCKLSGGC
  • 4. L12A07346|    From 39 To 71 E-value: 0.00000000001 Score: 60.1
        GLFSVVKGVLKGVGKNVAGSLLEQLKCKISGGC
  • 5. L13A016275    From 1 To 33 E-value: 0.00000000003 Score: 58.9
        GLFSVVKGVLKGVGKNVAGSLLEQLKCKISGGC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S. aureus  MIC:  49.77 μg/ml  (15 μM)  
  •   2  Target:  E. coli  MIC:  49.77 μg/ml  (15 μM)  
  •   3  Target:  E. coli  MIC:  49.77 μg/ml  (15 μM)  
  •   4  Target:  S. aureus  MIC:  49.77 μg/ml  (15 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Vaudry H.,Leprince J.,Nowotny N.,Kolodziejek J.,Conlon J.M.,
  •   Title:Cytolytic peptides belonging to the brevinin-1 and brevinin-2 families isolated from the skin of the Japanese brown frog, Rana dybowskii.
  •   Journal:Toxicon, 2007, 50, 746-756  [PubMed:17688900]

Comments

  •   Comments

    •     No comments found on LAMP database



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