Record in detail

lamp_id:L01A000206
Name:B2DYE_RANDY
FullName:Brevinin-2DYe
Source:Rana dybowskii
Mass:3675.4 Da
Sequence Length:37 aa
Isoelectric Point:10.23
Activity:Antibacterial
Sequence
GLFSVVTGVLKAVGKNVAKNVGGSLLEQLKCKISGGC
Function:Antimicrobial peptide. Active against the Gram-positive bacterium S.aureus (MIC=15 uM) and the Gram-negative bacterium E.coli (MIC=30 uM).

Top similar AMPs on LAMP
1. L01A000206 From 1 To 37 E-value: 0.00000000000001 Score: 70.5
GLFSVVTGVLKAVGKNVAKNVGGSLLEQLKCKISGGC
2. L02A000568 From 1 To 38 E-value: 0.0000000000003 Score: 65.9
GLFSVVTGVLKAVGKNVAKNVGGSLLEQLKCKKISGGC
3. L12A07360| From 42 To 78 E-value: 0.000000000007 Score: 60.8
GLLSVFKGVLKAAGKNVAKNVAGSLLDQLKCKISGGC
4. L12A07361| From 42 To 78 E-value: 0.00000000002 Score: 59.3
GLLSVFKGVLKTAGKNVAKNVAGSLLDQLKCKISGGC
5. L12A07178| From 42 To 78 E-value: 0.00000000002 Score: 59.3
GLLSVFKGVLKTAGKNVAKNVAGSLLDQLKCKISGGC

Antibacterial Activities
1 Target: [ Refer PubMed 17688900 :- S. aureus MIC: 55.13 μg/ml (14.9997 μM)
2 Target: E. coli ] MIC: 110.26 μg/ml (29.9995 μM)
3 Target: E. coli MIC: 61.7467 μg/ml (16.8 μM)
4 Target: S. aureus MIC: 24.9927 μg/ml (6.8 μM)

Reference
[1] Vaudry H.,Leprince J.,Nowotny N.,Kolodziejek J.,Conlon J.M.,
Title:Cytolytic peptides belonging to the brevinin-1 and brevinin-2 families isolated from the skin of the Japanese brown frog, Rana dybowskii.
Journal:Toxicon, 2007, 50, 746-756 [PubMed:17688900]
[2] Zhang D.-B.,Feng K.,Song S.-S.,Li Q.,Jin L.-L.,
Title:Characterization of antimicrobial peptides isolated from the skin of the Chinese frog, Rana dybowskii.
Journal:Comp. Biochem. Physiol., 2009, 154, 174-178 [PubMed:19539775]