Record in detail

lamp_id:L01A000214
Name:DEFI_APIME
FullName:Defensin-1
Source:Apis mellifera
Mass:5532.3 Da
Sequence Length:51 aa
Isoelectric Point:8.12
Activity:Antibacterial
Sequence
VTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKVGCICRKTSFKDLWDKYF
Function:Found in royal jelly and in hemolymph, potent antibacterial protein against Gram-positive bacteria at low concentration.

Top similar AMPs on LAMP
1. L01A000214 From 1 To 51 E-value: 3e-25 Score: 105
VTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKVGCICRKTSFKDLWDKYF
2. L02A000226 From 1 To 51 E-value: 2e-24 Score: 102
VTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKVGCICRKTSFKDLWDKRF
3. L13A022983 From 1 To 49 E-value: 1e-23 Score: 100
VTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKVGCICRKTSFKDLWDK
4. L03A000349 From 1 To 51 E-value: 2e-23 Score: 99.4
VTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKGVCICRKTSFKDLWDKYF
5. L12A07935| From 44 To 94 E-value: 2e-23 Score: 99
VTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKGVCICRKTSFKDLWDKRF

Reference
[1] Kawashima T.,Yaeshima T.,Fujiwara M.,Imai J.,Fujiwara S.,
Title:A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin.
Journal:J. Biol. Chem., 1990, 265, 11333-11337 [MEDLINE:90293084]
[2] Tempst P.,Casteels P.,Capaci T.,Zhang W.,Casteels-Josson K.,
Title:Acute transcriptional response of the honeybee peptide-antibiotics gene repertoire and required post-translational conversion of the precursor structures.
Journal:J. Biol. Chem., 1994, 269, 28569-28575 [MEDLINE:95050655]
[3] Simuth J.,Kopernicky J.,Bachanova K.,Albert S.,Klaudiny J.,
Title:Two structurally different defensin genes, one of them encoding a novel defensin isoform, are expressed in honeybee Apis mellifera.
Journal:Insect Biochem. Mol. Biol., 2005, 35, 11-22 [PubMed:15607651]
[4] Tingek S.,Rueppell O.,Hasselmann M.,Evans J.D.,Viljakainen L.,
Title:Rapid evolution of immune proteins in social insects.
Journal:Mol. Biol. Evol., 2009, 26, 1791-1801 [PubMed:19387012]