Record in detail

lamp_id:L01A000219
Name:PMP36_PIG
FullName:Antibacterial peptide PMAP-36
Source:Sus scrofa
Mass:4157.2 Da
Sequence Length:36 aa
Isoelectric Point:12.82
Activity:Antibacterial
Sequence
GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLGCG
Function:Exerts antimicrobial activity against both Gram-positive and negative bacteria. Its activity appears to be mediated by its ability to damage bacterial membranes.

Top similar AMPs on LAMP
1. L02A000370 From 2 To 37 E-value: 0.00000000000003 Score: 68.9
GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLGCG
2. L01A000219 From 1 To 36 E-value: 0.00000000000003 Score: 68.9
GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLGCG
3. L13A024076 From 1 To 35 E-value: 0.0000000000001 Score: 67
GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLGC
4. L13A023512 From 1 To 34 E-value: 0.00001 Score: 40
GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLG
5. L11A010644 From 1 To 24 E-value: 0.0001 Score: 37.4
GVFRRLRKVTRKVLKKIGKVLKWI

Antibacterial Activities
1 Target: Escherichia coli ML 35 MIC: 49.89 μg/ml (12.0009 μM)
2 Target: Escherichia coli ATCC 25922 MIC: 49.89 μg/ml (12.0009 μM)
3 Target: Salmonella typhimurium ATCC 14028 MIC: 199.55 μg/ml (48.0011 μM)
4 Target: P.seudomonas aeruginosa ATCC 25873 MIC: 12.47 μg/ml (2.99961 μM)
5 Target: Bacillus megaterium local isolate MIC: 12.47 μg/ml (2.99961 μM)
6 Target: Staphylococcus aureus ATCC 25923 MIC: 24.94 μg/ml (5.99923 μM)

Reference
[1] Zanetti M.,Gennaro R.,Tossi A.,Scocchi M.,Storici P.,
Title:Chemical synthesis and biological activity of a novel antibacterial peptide deduced from a pig myeloid cDNA.
Journal:FEBS Lett., 1994, 337, 303-307 [MEDLINE:94123775]