Record in detail
General Info
- lamp_id:L01A000249
- Name:AUR11_LITRA
- FullName:Aurein-1.1
- Source:Litoria raniformis
- Mass:1446.7 Da
- Sequence Length:13 aa
- Isoelectric Point:6.51
- Activity:Antibacterial,Anticancer
- Sequence
GLFDIIKKIAESI - Function:Antimicrobial activity against B.cereus, L.lactis, L.innocua and S.uberis. Probably acts by disturbing membrane functions with its amphipathic structure.
Cross-Linking
- Cross-linking
- 1 Database:APD 12
- 2 Database:CAMP CAMPSQ227
- 3 Database:DBAASP 772
- 4 Database:dbAMP dbAMP_03276
- 5 Database:DRAMP DRAMP01606
- 6 Database:SATPdb satpdb24748
- 7 Database:Uniprot P82386
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000249 From 1 To 13 E-value: 0.065 Score: 26.9
GLFDIIKKIAESI - 2. L13A027567 From 1 To 12 E-value: 0.14 Score: 25.8
GLFDIIKKIAES - 3. L12A03275| From 1 To 12 E-value: 0.16 Score: 25.8
GLFDIIKKIAES - 4. L01A000250 From 1 To 12 E-value: 0.16 Score: 25.8
GLFDIIKKIAES - 5. L13A024169 From 15 To 26 E-value: 0.19 Score: 25.4
GLFDIIKKIAES
Structure
- Domains
- 1 Name:Aurein_antimicrobial_peptide Interpro Link:IPR013157
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: B. cereus MIC: 50 μg/ml (34.5614 μM)
- 2 Target: L. lactis MIC: 25 μg/ml (17.2807 μM)
- 3 Target: L. innocua MIC: 100 μg/ml (69.1228 μM)
- 4 Target: S. uberis MIC: 100 μg/ml (69.1228 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Carver J.A.,Olver I.N.,Bowie J.H.,Wegener K.L.,Rozek T.,
- Title:The antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
- Journal:Eur. J. Biochem., 2000, 267, 5330-5341 [MEDLINE:20408845]
Comments
- Comments
No comments found on LAMP database