Record in detail


General Info

  • lamp_id:L01A000253
  • Name:AUR24_LITAU
  • FullName:Aurein-2.4
  • Source:Litoria aurea
  • Mass:1459.8 Da
  • Sequence Length:14 aa
  • Isoelectric Point:9.53
  • Activity:Antibacterial, ,Anticancer
  • Sequence
        FDIVKKVVGTIAGL
  • Function:Antimicrobial activity against B.cereus, L.lactis, L.innocua, M.luteus, S.aureus, S.epidermidis and S.uberis. Probably acts by disturbing membrane functions with its amphipathic structure. Shows anticancer activity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000253    From 1 To 14 E-value: 0.023 Score: 28.5
        FDIVKKVVGTIAGL
  • 2. L13A028615    From 3 To 16 E-value: 0.024 Score: 28.5
        FDIVKKVVGTIAGL
  • 3. L13A011030    From 3 To 16 E-value: 0.024 Score: 28.5
        FDIVKKVVGTIAGL
  • 4. L02A000017    From 3 To 16 E-value: 0.04 Score: 27.7
        FDIVKKVVGTLAGL
  • 5. L13A021776    From 1 To 13 E-value: 0.072 Score: 26.9
        FDIVKKVVGTIAG

Structure

  •   Domains
  •   1  Name:Aurein_antimicrobial_peptide    Interpro Link:IPR013157
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Carver J.A.,Olver I.N.,Bowie J.H.,Wegener K.L.,Rozek T.,
  •   Title:The antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
  •   Journal:Eur. J. Biochem., 2000, 267, 5330-5341  [MEDLINE:20408845]

Comments

  •   Comments

    •     No comments found on LAMP database



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