Record in detail
General Info
- lamp_id:L01A000255
- Name:AUR33_LITRA
- FullName:Aurein-3.3
- Source:Litoria raniformis
- Mass:1797.1 Da
- Sequence Length:17 aa
- Isoelectric Point:9.53
- Activity:Antibacterial, ,Anticancer,Anticancer
- Sequence
GLFDIVKKIAGHIVSSI - Function:Antimicrobial activity against L.lactis, M.luteus, P.multocida, S.aureus, S.epidermidis and S.uberis. Probably acts by disturbing membrane functions with its amphipathic structure. Shows anticancer activity.
Cross-Linking
- Cross-linking
- 1 Database:APD 22
- 2 Database:CAMP CAMPSQ233
- 3 Database:DBAASP 781
- 4 Database:dbAMP dbAMP_03288
- 5 Database:DRAMP DRAMP01618
- 6 Database:SATPdb satpdb13076
- 7 Database:Uniprot P82396
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000255 From 1 To 17 E-value: 0.0005 Score: 34.3
GLFDIVKKIAGHIVSSI - 2. L01A000622 From 1 To 17 E-value: 0.001 Score: 33.1
GLFDIVKKIAGHIASSI - 3. L12A06191| From 50 To 66 E-value: 0.002 Score: 32.3
GLFDIVKKIAGHIAGSI - 4. L01A000620 From 1 To 17 E-value: 0.004 Score: 31.2
GLFDIVKKIAGHIAGSI - 5. L13A014448 From 1 To 15 E-value: 0.007 Score: 30.4
FDIVKKIAGHIVSSI
Structure
- Domains
- 1 Name:Aurein_antimicrobial_peptide Interpro Link:IPR013157
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: Leuconostoc lactis MIC: 12 μg/ml (6.67742 μM)
- 2 Target: Micrococcus luteus MIC: 100 μg/ml (55.6452 μM)
- 3 Target: Pasteurella multocida MIC: 100 μg/ml (55.6452 μM)
- 4 Target: Staphylococcus aureus MIC: 100 μg/ml (55.6452 μM)
- 5 Target: Staphylococcus epidermidis MIC: 50 μg/ml (27.8226 μM)
- 6 Target: Streptococcus uberis MIC: 25 μg/ml (13.9113 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Carver J.A.,Olver I.N.,Bowie J.H.,Wegener K.L.,Rozek T.,
- Title:The antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
- Journal:Eur. J. Biochem., 2000, 267, 5330-5341 [MEDLINE:20408845]
Comments
- Comments
No comments found on LAMP database