Record in detail
General Info
- lamp_id:L01A000256
- Name:MCU11_LITGE
- FullName:Maculatin-1.1
- Source:Litoria genimaculata
- Mass:2146.6 Da
- Sequence Length:21 aa
- Isoelectric Point:7.72
- Activity:Antibacterial
- Sequence
GLFGVLAKVAAHVVPAIAEHF - Function:Maculatin-1.1 shows significant antibacterial activity against Gram-positive bacteria, less against Gram-negative bacteria. Maculatin-1.1.1 is inactive.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ234
- 2 Database:DBAASP 1824
- 3 Database:dbAMP dbAMP_03323
- 4 Database:DRAMP DRAMP01364
- 5 Database:SATPdb satpdb22175
- 6 Database:Uniprot P82066
- 7 Database:AMD MAC11_LITGE
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A000256 From 1 To 21 E-value: 0.000004 Score: 41.6
GLFGVLAKVAAHVVPAIAEHF - 2. L01A000257 From 1 To 21 E-value: 0.000005 Score: 41.2
GLFGVLAKVASHVVPAIAEHF - 3. L13A015737 From 1 To 21 E-value: 0.00001 Score: 40
GLFGVLAKVAAHVVPAIAKHF - 4. L13A029048 From 1 To 20 E-value: 0.00002 Score: 39.7
LFGVLAKVAAHVVPAIAEHF - 5. L11A005706 From 1 To 20 E-value: 0.00002 Score: 39.7
GLFGVLAKVAAHVVPAIAEH
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: S. aureus MIC: 6.01048 μg/ml (2.8 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Tyler M.J.,Bowie J.H.,Steinborner S.T.,Waugh R.J.,Rozek T.,
- Title:The maculatin peptides from the skin glands of the tree frog Litoria genimaculata. A comparison of the structures and antibacterial activities of maculatin 1.1 and caerin 1.1.
- Journal:J. Pept. Sci., 1998, 4, 111-115 [MEDLINE:98281937]
Comments
- Comments
No comments found on LAMP database