Record in detail
General Info
- lamp_id:L01A000277
- Name:CTHL4_BOVIN
- FullName:Cathelicidin-4
- Source:Bos taurus
- Mass:1907.3 Da
- Sequence Length:13 aa
- Isoelectric Point:12.51
- Activity:Antibacterial
- Sequence
ILPWKWPWWPWRR - Function:Potent microbicidal activity; active against S.aureus and E.coli.
Cross-Linking
- Cross-linking
- 1 Database:APD 150
- 2 Database:CAMP CAMPSQ254
- 3 Database:DBAASP 491
- 4 Database:dbAMP dbAMP_04768
- 5 Database:DRAMP DRAMP02857
- 6 Database:SATPdb satpdb10356
- 7 Database:Uniprot P33046
- 8 Database:AMD IND_BOVIN
- 9 Database:RAP RAPD0009
- 10 Database:RAP RAPD0016
- 11 Database:RAP RAPD0060
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A04769| From 1 To 13 E-value: 0.033 Score: 27.7
ILPWKWPWWPWRR - 2. L01A000277 From 1 To 13 E-value: 0.033 Score: 27.7
ILPWKWPWWPWRR - 3. L01A001503 From 1 To 13 E-value: 0.045 Score: 27.3
ILPWKWPWWPWRR - 4. L11A004816 From 2 To 13 E-value: 0.098 Score: 26.2
LPWKWPWWPWRR - 5. L11A004827 From 1 To 12 E-value: 0.1 Score: 26.2
ILPWKWPWWPWR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Zanetti M.,Romeo D.,Schneider C.,Storici P.,del Sal G.,
- Title:cDNA cloning of the neutrophil bactericidal peptide indolicidin.
- Journal:Biochem. Biophys. Res. Commun., 1992, 187, 467-472 [MEDLINE:92392368]
- [2] Smith W.,Tang Y.-Q.,Morris W.L.,Novotny M.J.,Selsted M.E.,
- Title:Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils.
- Journal:J. Biol. Chem., 1992, 267, 4292-4295 [MEDLINE:92165771]
- [3] Hancock R.E.,Friedrich C.L.,Rozek A.,
- Title:Structure of the bovine antimicrobial peptide indolicidin bound to dodecylphosphocholine and sodium dodecyl sulfate micelles.
- Journal:Biochemistry, 2000, 39, 15765-15774 [PubMed:11123901]
- [4] Park S.C.,Park Y.,Kim S.A.,Kim H.K.,Lee D.G.,
- Title:Fungicidal effect of indolicidin and its interaction with phospholipid membranes.
- Journal:Biochem. Biophys. Res. Commun., 2003, 305, 305-310 [PubMed:12745074]
Comments
- Comments
No comments found on LAMP database