Record in detail


General Info

  • lamp_id:L01A000287
  • Name:RUGA_GLARU
  • FullName:Rugosin-A
  • Source:Glandirana rugosa
  • Mass:3440 Da
  • Sequence Length:33 aa
  • Isoelectric Point:9.55
  • Activity:Antibacterial
  • Sequence
        GLLNTFKDWAISIAKGAGKGVLTTLSCKLDKSC
  • Function:Has antibacterial activity against Gram-positive bacteria.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000287    From 1 To 33 E-value: 0.0000000000002 Score: 66.2
        GLLNTFKDWAISIAKGAGKGVLTTLSCKLDKSC
  • 2. L12A07302|    From 44 To 76 E-value: 0.00000002 Score: 49.3
        GLLDTLKNVAIGVAKGAGVGVLNALSCKLDKSC
  • 3. L01A003982    From 1 To 33 E-value: 0.00000003 Score: 49.3
        GVLDTFKDVAIGVAKGAGTGVLKALLCKLDKSC
  • 4. L13A011328    From 1 To 33 E-value: 0.00000003 Score: 48.9
        GLLDTLKNVAIGVAKGAGVGVLNALSCKLDKSC
  • 5. L13A024779    From 1 To 33 E-value: 0.00000008 Score: 47.4
        GLLDVLKNVAIGVAKGAGVGVLNALSCKLDKSC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Staphylococcus aureus 209P  MIC:  6.25 μg/ml  (1.81686 μM)  
  •   2  Target:  Bacillus subtilis ATCC6633  MIC:  12.5 μg/ml  (3.63372 μM)  
  •   3  Target:  Micrococcus luteus ATCC9341  MIC:  25 μg/ml  (7.26744 μM)  
  •   4  Target:  Streptococcus pyogenes COOK  MIC:  50 μg/ml  (14.5349 μM)  
  •   5  Target:  Eschericia coli NIHJ  MIC:  100 μg/ml  (29.0698 μM)  
  •   6  Target:  Pseudomonas aeruginosa PAO-1  MIC:  100 μg/ml  (29.0698 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Tatemoto K.,Kagegawa T.,Ohe Y.,Suzuki S.,
  •   Title:Isolation and characterization of novel antimicrobial peptides, rugosins A, B and C, from the skin of the frog, Rana rugosa.
  •   Journal:Biochem. Biophys. Res. Commun., 1995, 212, 249-254  [MEDLINE:95336450]

Comments

  •   Comments

    •     No comments found on LAMP database



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