Record in detail
General Info
- lamp_id:L01A000296
- Name:DEF3A_RAT
- FullName:Neutrophil antibiotic peptide NP-3
- Source:Rattus norvegicus
- Mass:3271.8 Da
- Sequence Length:29 aa
- Isoelectric Point:8.89
- Activity:Antibacterial, Antifungal, Antiviral
- Sequence
CSCRTSSCRFGERLSGACRLNGRIYRLCC - Function:Active in vitro against S.aureus, fungi, Gram-positive and Gram-negative bacteria and to a lesser extent against an enveloped virus.
Cross-Linking
- Cross-linking
- 1 Database:APD 224
- 2 Database:CAMP CAMPSQ273
- 3 Database:dbAMP dbAMP_00928
- 4 Database:DRAMP DRAMP03421
- 5 Database:SATPdb satpdb15433
- 6 Database:Uniprot Q62713
- 7 Database:DEF DEF157
- 8 Database:DEF DEF174
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000287 From 59 To 87 E-value: 0.000000000006 Score: 61.2
CSCRTSSCRFGERLSGACRLNGRIYRLCC - 2. L12A09232| From 59 To 87 E-value: 0.000000000006 Score: 61.2
CSCRTSSCRFGERLSGACRLNGRIYRLCC - 3. L01A000296 From 1 To 29 E-value: 0.0000000001 Score: 57
CSCRTSSCRFGERLSGACRLNGRIYRLCC - 4. L03A000284 From 64 To 92 E-value: 0.0000006 Score: 44.7
CYCRIGACVSGERLTGACGLNGRIYRLCC - 5. L05ADEF377 From 62 To 90 E-value: 0.000002 Score: 43.1
CSCRIGTCVSGEWLSWVCRINGRIYRLCC
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Selsted M.E.,Ganz T.,Szklarek D.,Harwig S.S.S.L.,Eisenhauer P.B.,
- Title:Purification and antimicrobial properties of three defensins from rat neutrophils.
- Journal:Infect. Immun., 1989, 57, 2021-2027 [MEDLINE:89277517]
- [2] Ouellette A.J.,Banaiee N.,Yuan J.,Wang M.-S.C.,Yount N.Y.,
- Title:Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis.
- Journal:J. Immunol., 1995, 155, 4476-4484 [MEDLINE:96025910]
Comments
- Comments
No comments found on LAMP database