Record in detail


General Info

  • lamp_id:L01A000306
  • Name:GGN5_GLARU
  • FullName:Gaegurin-5
  • Source:Glandirana rugosa
  • Mass:2571.2 Da
  • Sequence Length:24 aa
  • Isoelectric Point:10.35
  • Activity:Antibacterial, Antifungal, Antiparasitic
  • Sequence
        FLGALFKVASKVLPSVFCAITKKC
  • Function:Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A07100|    From 42 To 65 E-value: 0.00000002 Score: 49.7
        FLGALFKVASKVLPSVFCAITKKC
  • 2. L01A000306    From 1 To 24 E-value: 0.00000005 Score: 48.1
        FLGALFKVASKVLPSVFCAITKKC
  • 3. L03A000019    From 1 To 24 E-value: 0.0000005 Score: 44.7
        FLGALFKVASKVLPSVKCAITKKC
  • 4. L13A026152    From 1 To 24 E-value: 0.00006 Score: 37.7
        FLPAVIRVAANVLPTVFCAITKKC
  • 5. L01A003383    From 1 To 24 E-value: 0.00007 Score: 37.7
        FMGGLIKAATKALPAAFCAITKKC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_1    Interpro Link:IPR012520
  •   2  Name:Brevinin    Interpro Link:IPR004275
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  Micrococcus luteus  MIC:  2.5 μg/ml  (0.972309 μM)  
  •   2  Target:  Staphylococcus epidermidis  MIC:  10 μg/ml  (3.88923 μM)  
  •   3  Target:  Bacillus subtilis  MIC:  10 μg/ml  (3.88923 μM)  
  •   4  Target:  Klebsiella pneumoniae  MIC:  50 μg/ml  (19.4462 μM)  
  •   5  Target:  Shigella dysentariae  MIC:  50 μg/ml  (19.4462 μM)  
  •   6  Target:  Pseudomonas putida  MIC:  50 μg/ml  (19.4462 μM)  
  •   7  Target:  Pseudomonas aeruginosa  MIC:  100 μg/ml  (38.8923 μM)  
  •   8  Target:  Eshchericia coli  MIC:  50 μg/ml  (19.4462 μM)  
  •   9  Target:  Saccharomyces cerevisiae  MIC:  50 μg/ml  (19.4462 μM)  
  •   10  Target:  Candida albicans  MIC:  50 μg/ml  (19.4462 μM)  
  •   11  Target:  Salmonella typhimurium  MIC:  200 μg/ml  (77.7847 μM)  
  •   12  Target:  Proteus mirabilis  MIC:  200 μg/ml  (77.7847 μM)  
  •   13  Target:  Serratia marcescens  MIC:  200 μg/ml  (77.7847 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lee B.J.,Jung J.-E.,Park J.M.,
  •   Title:Antimicrobial peptides from the skin of a Korean frog, Rana rugosa.
  •   Journal:Biochem. Biophys. Res. Commun., 1994, 205, 948-954  [MEDLINE:95091844]

Comments

  •   Comments

  •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: