Record in detail
General Info
- lamp_id:L01A000306
- Name:GGN5_GLARU
- FullName:Gaegurin-5
- Source:Glandirana rugosa
- Mass:2571.2 Da
- Sequence Length:24 aa
- Isoelectric Point:10.35
- Activity:Antibacterial, Antifungal, Antiparasitic
- Sequence
FLGALFKVASKVLPSVFCAITKKC - Function:Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.
Cross-Linking
- Cross-linking
- 1 Database:APD 89
- 2 Database:CAMP CAMPSQ283
- 3 Database:DBAASP 918
- 4 Database:dbAMP dbAMP_01894
- 5 Database:DRAMP DRAMP02295
- 6 Database:SATPdb satpdb16036
- 7 Database:Uniprot P80399
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A07100| From 42 To 65 E-value: 0.00000002 Score: 49.7
FLGALFKVASKVLPSVFCAITKKC - 2. L01A000306 From 1 To 24 E-value: 0.00000005 Score: 48.1
FLGALFKVASKVLPSVFCAITKKC - 3. L03A000019 From 1 To 24 E-value: 0.0000005 Score: 44.7
FLGALFKVASKVLPSVKCAITKKC - 4. L13A026152 From 1 To 24 E-value: 0.00006 Score: 37.7
FLPAVIRVAANVLPTVFCAITKKC - 5. L01A003383 From 1 To 24 E-value: 0.00007 Score: 37.7
FMGGLIKAATKALPAAFCAITKKC
Activity
- Antibacterial Activities
- 1 Target: Micrococcus luteus MIC: 2.5 μg/ml (0.972309 μM)
- 2 Target: Staphylococcus epidermidis MIC: 10 μg/ml (3.88923 μM)
- 3 Target: Bacillus subtilis MIC: 10 μg/ml (3.88923 μM)
- 4 Target: Klebsiella pneumoniae MIC: 50 μg/ml (19.4462 μM)
- 5 Target: Shigella dysentariae MIC: 50 μg/ml (19.4462 μM)
- 6 Target: Pseudomonas putida MIC: 50 μg/ml (19.4462 μM)
- 7 Target: Pseudomonas aeruginosa MIC: 100 μg/ml (38.8923 μM)
- 8 Target: Eshchericia coli MIC: 50 μg/ml (19.4462 μM)
- 9 Target: Saccharomyces cerevisiae MIC: 50 μg/ml (19.4462 μM)
- 10 Target: Candida albicans MIC: 50 μg/ml (19.4462 μM)
- 11 Target: Salmonella typhimurium MIC: 200 μg/ml (77.7847 μM)
- 12 Target: Proteus mirabilis MIC: 200 μg/ml (77.7847 μM)
- 13 Target: Serratia marcescens MIC: 200 μg/ml (77.7847 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lee B.J.,Jung J.-E.,Park J.M.,
- Title:Antimicrobial peptides from the skin of a Korean frog, Rana rugosa.
- Journal:Biochem. Biophys. Res. Commun., 1994, 205, 948-954 [MEDLINE:95091844]
Comments
- Comments
No comments found on LAMP database