Record in detail
General Info
- lamp_id:L01A000307
- Name:SAPB_SARPE
- FullName:Sapecin-B
- Source:Sarcophaga peregrina
- Mass:4003.8 Da
- Sequence Length:34 aa
- Isoelectric Point:8.62
- Activity:Antibacterial
- Sequence
LTCEIDRSLCLLHCRLKGYLRAYCSQQKVCRCVQ - Function:Sapecins, which are potent bactericidal proteins, are produced in response to injury. Sapecin B is cytotoxic to Gram-positive bacteria.
Cross-Linking
- Cross-linking
- 1 Database:APD 228
- 2 Database:CAMP CAMPSQ284
- 3 Database:DBAASP 5158
- 4 Database:dbAMP dbAMP_06059
- 5 Database:DRAMP DRAMP03083
- 6 Database:SATPdb satpdb23494
- 7 Database:Uniprot P31529
- 8 Database:AMD SAPB_SARPE
- 9 Database:DEF DEF58
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A07870| From 55 To 88 E-value: 0.000000000000003 Score: 72.4
LTCEIDRSLCLLHCRLKGYLRAYCSQQKVCRCVQ - 2. L01A000307 From 1 To 34 E-value: 0.00000000000004 Score: 68.6
LTCEIDRSLCLLHCRLKGYLRAYCSQQKVCRCVQ - 3. L13A023526 From 1 To 32 E-value: 0.0000008 Score: 44.3
LTCNIDRSFCLAHCLLRGYKRGFCTVKKICVC - 4. L13A016532 From 2 To 32 E-value: 0.00004 Score: 38.5
TCSFSSALCVVHCRVRGYPDGYCSRKGICTC - 5. L05ADEF399 From 51 To 84 E-value: 0.002 Score: 33.1
FTCDIWQNQAACAIHCIANGFRGGYCNAQKVCVC
Structure
- Domains
- 1 Name:Defensin_invertebrate/fungal Interpro Link:IPR001542
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Natori S.,Yamada K.,
- Title:Purification, sequence and antibacterial activity of two novel sapecin homologues from Sarcophaga embryonic cells: similarity of sapecin B to charybdotoxin.
- Journal:Biochem. J., 1993, 291, 275-279 [MEDLINE:93228618]
- [2] Natori S.,Kurata S.,Lee S.-R.,
- Title:Molecular cloning of cDNA for sapecin B, an antibacterial protein of Sarcophaga, and its detection in larval brain.
- Journal:FEBS Lett., 1995, 368, 485-487 [MEDLINE:95361929]
Comments
- Comments
No comments found on LAMP database