Record in detail


General Info

  • lamp_id:L01A000307
  • Name:SAPB_SARPE
  • FullName:Sapecin-B
  • Source:Sarcophaga peregrina
  • Mass:4003.8 Da
  • Sequence Length:34 aa
  • Isoelectric Point:8.62
  • Activity:Antibacterial
  • Sequence
        LTCEIDRSLCLLHCRLKGYLRAYCSQQKVCRCVQ
  • Function:Sapecins, which are potent bactericidal proteins, are produced in response to injury. Sapecin B is cytotoxic to Gram-positive bacteria.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A07870|    From 55 To 88 E-value: 0.000000000000003 Score: 72.4
        LTCEIDRSLCLLHCRLKGYLRAYCSQQKVCRCVQ
  • 2. L01A000307    From 1 To 34 E-value: 0.00000000000004 Score: 68.6
        LTCEIDRSLCLLHCRLKGYLRAYCSQQKVCRCVQ
  • 3. L13A023526    From 1 To 32 E-value: 0.0000008 Score: 44.3
        LTCNIDRSFCLAHCLLRGYKRGFCTVKKICVC
  • 4. L13A016532    From 2 To 32 E-value: 0.00004 Score: 38.5
        TCSFSSALCVVHCRVRGYPDGYCSRKGICTC
  • 5. L05ADEF399    From 51 To 84 E-value: 0.002 Score: 33.1
        FTCDIWQNQAACAIHCIANGFRGGYCNAQKVCVC

Structure

  •   Domains
  •   1  Name:Defensin_invertebrate/fungal    Interpro Link:IPR001542
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Natori S.,Yamada K.,
  •   Title:Purification, sequence and antibacterial activity of two novel sapecin homologues from Sarcophaga embryonic cells: similarity of sapecin B to charybdotoxin.
  •   Journal:Biochem. J., 1993, 291, 275-279  [MEDLINE:93228618]
  •   [2]  Natori S.,Kurata S.,Lee S.-R.,
  •   Title:Molecular cloning of cDNA for sapecin B, an antibacterial protein of Sarcophaga, and its detection in larval brain.
  •   Journal:FEBS Lett., 1995, 368, 485-487  [MEDLINE:95361929]

Comments

  •   Comments

  •     No comments found on LAMP database



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