Record in detail

General Info

lamp_id:L01A000316
Name:JAP1_RANJA
FullName:Japonicin-1
Source:Rana japonica
Mass:1650.1 Da
Sequence Length:14 aa
Isoelectric Point:8.82
Activity:Antibacterial
Sequence
FFPIGVFCKIFKTC
Function:Antibacterial activity against the Gram-negative bacterium E.coli and the Gram-positive bacterium S.aureus.

Cross-Linking

Cross-linking
1 Database:APD 357
2 Database:CAMP CAMPSQ293
3 Database:DBAASP 1644
4 Database:dbAMP dbAMP_01689
5 Database:DRAMP DRAMP01244
6 Database:SATPdb satpdb24195
7 Database:Uniprot P83305
8 Database:AMD JAP1_RANJA

Top similar AMPs

Top similar AMPs on LAMP
1. L01A000316 From 1 To 14 E-value: 0.006 Score: 30.4
FFPIGVFCKIFKTC
2. L12A07144| From 48 To 61 E-value: 0.59 Score: 23.9
FFPLALLCKVFKKC
3. L02A001455 From 1 To 14 E-value: 0.71 Score: 23.5
FFPLALLCKVFKKC
4. L13A024691 From 1 To 13 E-value: 2.1 Score: 21.9
FPLALLCKVFKKC
5. L12A06957| From 68 To 76 E-value: 2.7 Score: 21.6
IFCKIFKTC

Structure

Domains

Structures

Activity

Antibacterial Activities
1 Target: E.coli MIC: 49.5 μg/ml (29.9982 μM)
2 Target: S.aureus MIC: 165.01 μg/ml (100 μM)
3 Target: E. coli MIC: 49.503 μg/ml (30 μM)
4 Target: S. aureus MIC: 165.01 μg/ml (100 μM)

Toxicity

Toxicity

Reference

Reference
[1] Conlon J.M.,Knoop F.C.,Iwamuro S.,Soto A.,Isaacson T.,
Title:Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica.
Journal:Peptides, 2002, 23, 419-425 [MEDLINE:21826910]

Comments

Comments