Record in detail


General Info

  • lamp_id:L01A000322
  • Name:AB27_CYPCA
  • FullName:27 kDa antibacterial protein
  • Source:Cyprinus carpio
  • Mass:1966.1 Da
  • Sequence Length:19 aa
  • Isoelectric Point:3.83
  • Activity:Antibacterial
  • Sequence
        GIGGKPVQTAFVDNDGIYD
  • Function:Has antibacterial activity. It inhibits fish bacterial pathogens, A.hydrophila and M.luteus, and also E.coli, P.fluorescens and S.aureus. Forms large ion channels responsible for disrupting the cellular envelope of bacteria leading to cell lysis.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000322    From 1 To 19 E-value: 0.000006 Score: 40.8
        GIGGKPVQTAFVDNDGIYD

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  A. hydrophila  MIC:  5 μg/ml  (2.54311 μM)  
  •   2  Target:  M. luteus  MIC:  5 μg/ml  (2.54311 μM)  
  •   3  Target:  E. coli  MIC:  5 μg/ml  (2.54311 μM)  
  •   4  Target:  P. fluorescens  MIC:  10 μg/ml  (5.08621 μM)  
  •   5  Target:  S. aureus  MIC:  5 μg/ml  (2.54311 μM)  

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Gagnon J.,Saint N.,Saglio P.,Orange N.,Lemaitre C.,
  •   Title:Characterization and ion channel activities of novel antibacterial proteins from the skin mucosa of carp (Cyprinus carpio).
  •   Journal:Eur. J. Biochem., 1996, 240, 143-149  [MEDLINE:96390874]

Comments

  •   Comments

  •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: