Record in detail

General Info

lamp_id:L01A000361
Name:Dermaseptin-1
FullName:Dermaseptin-1
Source:Phyllomedusa sauvagii (painted-belly leaf frog)
Mass:3455.1 Da
Sequence Length:34 aa
Isoelectric Point:10.8
Activity:Antibacterial, Antifungal
Sequence
ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Function:

Cross-Linking

Cross-linking
1 Database:APD 157
2 Database:CAMP CAMPSQ332
3 Database:DBAASP 991
4 Database:dbAMP dbAMP_00393
5 Database:DRAMP DRAMP01668
6 Database:SATPdb satpdb28956
7 Database:Uniprot P24302
8 Database:AMD DMS1_PHYSA

Top similar AMPs

Top similar AMPs on LAMP
1. L12A06612| From 46 To 79 E-value: 0.00000000000004 Score: 68.2
ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
2. L01A000361 From 1 To 34 E-value: 0.0000000000003 Score: 65.5
ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
3. L12A06611| From 45 To 78 E-value: 0.00000000009 Score: 57.4
AMWKDVLKKIGTVALHAGKAALGAVADTISQGEQ
4. L12A06182| From 45 To 78 E-value: 0.0000000001 Score: 57.4
AMWKDVLKKIGTVALHAGKAALGAVADTISQGEQ
5. L11A012112 From 1 To 31 E-value: 0.0000000001 Score: 57
ALWKTMLKKLGTVALHAGKAALGAVADTISQ

Structure

Domains

Structures

Activity

Antibacterial Activities
1 Target: Microsporum canis IP 11 94 MIC: 50 μg/ml (14.4714 μM)
2 Target: Tricophyton rubrum IP 1400-82 MIC: 100 μg/ml (28.9427 μM)
3 Target: Arthroderma simii IP 1063-74 MIC: 100 μg/ml (28.9427 μM)
4 Target: Aspergillus fumigatus IP 1025-70 MIC: 100 μg/ml (28.9427 μM)
5 Target: Aerornonas caviae IP 67-16 T MIC: 50 μg/ml (14.4714 μM)
6 Target: Escherichia coli IP 76-24 MIC: 5 μg/ml (1.44714 μM)
7 Target: Nocardia brasiliensis IP 16-80 MIC: 200 μg/ml (57.8854 μM)
8 Target: Cryptococcus neoformans IP 960-67 MIC: 15 μg/ml (4.34141 μM)
9 Target: Cryptococcus neoformans IP 962-67 MIC: 15 μg/ml (4.34141 μM)
10 Target: Candida albicans IP 884-65 MIC: 60 μg/ml (17.3656 μM)
11 Target: E. coli MIC: 3.4551 μg/ml (1 μM)
12 Target: S. aureus MIC: 17.2755 μg/ml (5 μM)

Toxicity

Toxicity

Reference

Reference

Comments

Comments