Record in detail


General Info

  • lamp_id:L01A000419
  • Name:DMS5_PHYBI
  • FullName:Dermaseptin-B5
  • Source:Phyllomedusa bicolor
  • Mass:2704.2 Da
  • Sequence Length:26 aa
  • Isoelectric Point:10.33
  • Activity:Antibacterial
  • Sequence
        GLWNKIKEAASKAAGKAALGFVNEMV
  • Function:Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000419    From 1 To 26 E-value: 0.000000005 Score: 51.6
        GLWNKIKEAASKAAGKAALGFVNEMV
  • 2. L03A000048    From 1 To 25 E-value: 0.0000007 Score: 44.3
        GLWNKIKEAA-KSAGKAALGFVNEMV
  • 3. L13A025397    From 1 To 25 E-value: 0.000005 Score: 41.6
        GLWSKIKEAA-KTAGKAAMGFVNEMV
  • 4. L13A011220    From 1 To 25 E-value: 0.000005 Score: 41.6
        GLWSKIKEAA-KTAGKAAMGFVNEMV
  • 5. L01A002484    From 24 To 48 E-value: 0.00002 Score: 39.3
        GLWSKIKEAA-KTAGKMAMGFVNDMV

Structure

  •   Domains
  •   1  Name:Dermaseptin    Interpro Link:IPR022731
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Le Caer J.-P.,Vouille V.,Mester J.,Amiche M.,Charpentier S.,
  •   Title:Structure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics.
  •   Journal:J. Biol. Chem., 1998, 273, 14690-14697  [MEDLINE:98278974]

Comments

  •   Comments

    •     No comments found on LAMP database



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