Record in detail


General Info

  • lamp_id:L01A000435
  • Name:BR1LA_RANLU
  • FullName:Brevinin-1La
  • Source:Rana luteiventris
  • Mass:2548.3 Da
  • Sequence Length:24 aa
  • Isoelectric Point:9.67
  • Activity:Antibacterial
  • Sequence
        FLPMLAGLAASMVPKLVCLITKKC
  • Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A000435    From 1 To 24 E-value: 0.00000004 Score: 48.5
        FLPMLAGLAASMVPKLVCLITKKC
  • 2. L01A000436    From 1 To 24 E-value: 0.0000001 Score: 47
        FLPMLAGLAASMVPKFVCLITKKC
  • 3. L11A013306    From 1 To 24 E-value: 0.000004 Score: 42
        FLPILAGLAANLVPKLICSITKKC
  • 4. L02A001723    From 1 To 24 E-value: 0.000005 Score: 41.6
        FFPMLAGVAARVVPKVICLITKKC
  • 5. L13A010541    From 1 To 24 E-value: 0.000007 Score: 40.8
        FLPMLAGLAANFLPKIVCKITKKC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_1    Interpro Link:IPR012520
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  E. coli  MIC:  127.415 μg/ml  (50 μM)  
  •   2  Target:  S. aureus  MIC:  15.2898 μg/ml  (6 μM)  

Toxicity

  •   Toxicity

Reference

  •   Reference
  •   [1]  Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
  •   Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
  •   Journal:Eur. J. Biochem., 2000, 267, 894-900  [MEDLINE:20117700]

Comments

  •   Comments

  •     No comments found on LAMP database



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